SCHEMBL178801

SCHEMBL178801

O=C(O)CCCNC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.90

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.90
HTT P42858 1/20 0.58
EPHX2 P34913 1/20 0.50
CASP3 P42574 2/20 0.47
FABP7 O15540 1/20 0.46
FABP5 Q01469 1/20 0.46
ATM Q13315 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29792075 1.00 KMT2A (0.90) KMT2AHTTEPHX2CASP3FABP7
SCHEMBL29370234 1.00 KMT2A (0.90) KMT2AHTTEPHX2CASP3FABP7
Water SCHEMBL21809392 0.99 KMT2A (0.88) KMT2AHTTEPHX2CASP3FABP7
SCHEMBL97174 0.96 KMT2A (0.97) KMT2AHTTEPHX2CASP3FABP7
SCHEMBL29482640 0.96 KMT2A (0.97) KMT2AHTTEPHX2CASP3FABP7
SCHEMBL2182769 0.95 KMT2A (1.00) KMT2AHTTEPHX2CASP3FABP7
SCHEMBL178760 0.95 KMT2A (1.00) KMT2AHTTEPHX2CASP3FABP7
SCHEMBL178762 0.95 KMT2A (1.00) KMT2AHTTEPHX2CASP3FABP7
SCHEMBL178759 0.95 KMT2A (1.00) KMT2AHTTEPHX2CASP3FABP7
SCHEMBL178758 0.95 KMT2A (1.00) KMT2AHTTEPHX2CASP3FABP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 290 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115703736-A Multi-target inhibitors targeting HDAC and NAD synthesis and uses thereof 中国海洋大学 2023-02-17 CN claimed
EP-1506970-A1 COMPOUNDS WHICH CAN BLOCK THE RESPONSE TO CHEMICAL SUBSTANCES OR THERMAL STIMULI OR MEDIATORS OF INFLAMMATION OF NOCICEPTORS, PRODUCTION METHOD THEREOF AND COMPOSITIONS CONTAINING SAME Diverdrugs, S.L. (ES) 2005-02-16 EP claimed
US-6140493-A BIFUNCTIONAL SOLID SUPPORT HAVING A PLURALITY OF AMINE ACTIVE SITES AND A PLURALITY OF HYDROXYL ACTIVE SITES; FOR SOLID PHASE SYNTHESIS AFFYMAX TECHNOLOGIES N.V. (GB) 2000-10-31 US claimed
EP-0604552-A1 METHOD OF SYNTHESIZING DIVERSE COLLECTIONS OF OLIGOMERS. AFFYMAX TECH NV (AN) 1994-07-06 EP claimed
EP-0604552-A4 METHOD OF SYNTHESIZING DIVERSE COLLECTIONS OF OLIGOMERS. AFFYMAX TECH NV (AN) 1993-08-02 EP claimed
WO-1993006121-A1 METHOD OF SYNTHESIZING DIVERSE COLLECTIONS OF OLIGOMERS AFFYMAX TECHNOLOGIES N.V. (NL) 1993-04-01 WO claimed
EP-3455234-B1 SECO MACROLIDE COMPOUNDS SELVITA D O O (HR) 2026-04-01 EP disclosed
EP-3966226-B1 MASP INHIBITORY COMPOUNDS AND USES THEREOF BAYER AG (DE) 2025-12-24 EP disclosed
US-12503491-B2 MASP inhibitory compounds and uses thereof BAYER AKTIENGESELLSCHAFT (DE) 2025-12-23 US disclosed
WO-2025224092-A1 PEPTIDE-BASED RADIOPHARMACEUTICALS FOR NON-INVASIVE IMAGING OF THE FUNCTIONAL LIVER RESERVE MEDIZINISCHE UNIVERSITÄT INNSBRUCK (AT) 2025-10-30 WO disclosed
EP-4640240-A1 PEPTIDE-BASED RADIOPHARMACEUTICALS FOR NON-INVASIVE IMAGING OF THE FUNCTIONAL LIVER RESERVE Medizinische Universität Innsbruck (AT) 2025-10-29 EP disclosed
US-20250297258-A1 OLIGONUCLEOTIDE-BASED DELIVERY VEHICLE FOR OLIGONUCLEOTIDES AGENTS AND METHODS OF USE THEREOF RACTIGEN THERAPEUTICS (CN) 2025-09-25 US disclosed
US-20250243540-A1 PROBE RELATED REAGENTS AND METHODS BRENTANO BIOTECHNOLOGY ASSOCIATES (US) 2025-07-31 US disclosed
WO-1993006121-A1 METHOD OF SYNTHESIZING DIVERSE COLLECTIONS OF OLIGOMERS AFFYMAX TECHNOLOGIES N.V. (NL) 1993-04-01 WO disclosed
WO-1992002641-A1 PSORALEN CONJUGATED METHYLPHOSPHONATE OLIGONUCLEOTIDES AS THERAPEUTIC AGENTS FOR CHRONIC MYELOGENOUS LEUKEMIA GENTA INCORPORATED (US) 1992-02-20 WO disclosed
WO-1992002542-A1 PEPTIDES AND PHARMACEUTICAL COMPOSITIONS HAVING GLYCOPROTEIN HORMONE AGONISTIC OR ANTAGONISTIC ACTIVITY STICHTING CENTRAAL DIERGENEESKUNDIG INSTITUUT (NL) 1992-02-20 WO disclosed
WO-1992002532-A1 IMPROVED NON-NUCLEOTIDE-BASED LINKER REAGENTS FOR OLIGOMERS GENTA INCORPORATED (US) 1992-02-20 WO disclosed
EP-0339695-A2 A process for preparing an antigenic or immunogenic conjugate as well as the use of such conjugates STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) 1989-11-02 EP disclosed
EP-0313219-A2 Non-nucleotide linking reagents for nucleotide probes GEN-PROBE INCORPORATED (US) 1989-04-26 EP disclosed
WO-1989002439-A1 NON-NUCLEOTIDE LINKING REAGENTS FOR NUCLEOTIDE PROBES ML TECHNOLOGY VENTURES, L.P. (US) 1989-03-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250297258-A1 OLIGONUCLEOTIDE-BASED DELIVERY VEHICLE FOR OLIGONUCLEOTIDES AGENTS AND METHODS OF USE THEREOF MTREX, DCLRE1B, ADAR KMT2A 2608/4885HTT 1995/4885EPHX2 2274/4885
US-12503491-B2 MASP inhibitory compounds and uses thereof MASP2, SERPINB1, SPINT2 KMT2A 4690/4885HTT 4056/4885EPHX2 4299/4885
US-20250243540-A1 PROBE RELATED REAGENTS AND METHODS DNTT, NCL, NT5C3B KMT2A 4217/4885HTT 2257/4885EPHX2 1363/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.