Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 12/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7100323 | 0.93 | ADORA2A (0.52) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL7100326 | 0.93 | ADORA2A (0.52) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL7099675 | 0.90 | ADORA2A (0.43) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL7099674 | 0.90 | ADORA2A (0.43) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL7098429 | 0.87 | ADORA2A (0.55) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL7151509 | 0.87 | ADORA2A (0.43) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL7104801 | 0.87 | ADORA2A (0.43) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL7099680 | 0.86 | ADORA1 (0.57) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL7204932 | 0.86 | ADORA2A (0.51) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL7569540 | 0.85 | ADORA2A (0.51) | ADORA2AADORA3ADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1090023-B1 | 2-(PURIN-9-YL)-TETRAHYDROFURAN-3,4-DIOL DERIVATIVES | GLAXO GROUP LTD (GB) | 2003-09-10 | — | — | EP | claimed |
| EP-1090023-B1 | 2-(PURIN-9-YL)-TETRAHYDROFURAN-3,4-DIOL DERIVATIVES | GLAXO GROUP LTD (GB) | 2003-09-10 | — | — | EP | disclosed |