Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RELA | Q04206 | 4/20 | 0.61 |
| ▸ | PPARA | Q07869 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31299681 | 1.00 | RELA (0.61) | RELAPPARAALDH1A1TSHRCA2 | |
| SCHEMBL7100793 | 1.00 | RELA (0.61) | RELAPPARAALDH1A1TSHRCA2 | |
| SCHEMBL7101496 | 0.94 | RELA (0.54) | RELAPPARAALDH1A1TSHRCA2 | |
| SCHEMBL7694320 | 0.90 | RELA (0.71) | RELAPPARACA2CA1EPHX1 | |
| SCHEMBL7685651 | 0.90 | RELA (0.71) | RELAPPARACA2CA1EPHX1 | |
| SCHEMBL8468160 | 0.90 | RELA (0.71) | RELAPPARACA2CA1EPHX1 | |
| SCHEMBL9609767 | 0.90 | RELA (0.71) | RELAPPARACA2CA1EPHX1 | |
| SCHEMBL18572502 | 0.90 | RELA (0.71) | RELAPPARACA2CA1EPHX1 | |
| SCHEMBL7688960 | 0.90 | RELA (0.71) | RELAPPARACA2CA1EPHX1 | |
| SCHEMBL7109056 | 0.90 | RELA (0.71) | RELAPPARACA2CA1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020443-B1 | PROCESS FOR PRODUCING PIPERAZINESULFONAMIDE DERIVATIVES AND SALTS THEREOF | AZWELL INC (JP) | 2003-09-10 | — | — | EP | disclosed |
| US-6172228-B1 | Process for producing piperazinesulfonamide derivatives and salts thereof | AZWELL INC. (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-1020443-A1 | PROCESS FOR PRODUCING PIPERAZINESULFONAMIDE DERIVATIVES AND SALTS THEREOF | Azwell Inc. (JP) | 2000-07-19 | — | — | EP | disclosed |
| EP-1020437-A1 | PROCESS FOR PRODUCING HALOGENOALKYLSULFONAMIDE DERIVATIVES | Azwell Inc. (JP) | 2000-07-19 | — | — | EP | disclosed |