Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | GRN | P28799 | 3/20 | 0.35 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 5/20 | 0.32 |
| ▸ | PPARG | P37231 | 4/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7102139 | 0.98 | CYP2D6 (0.38) | CYP2D6MEN1GAAKMT2AHDAC3 | |
| SCHEMBL7213859 | 0.88 | GRN (0.36) | MEN1GAAKMT2AGRNSORT1 | |
| SCHEMBL10253834 | 0.87 | CYP2D6 (0.39) | CYP2D6MEN1GAAKMT2AHDAC3 | |
| SCHEMBL7099887 | 0.82 | GRN (0.39) | GRNSORT1 | |
| SCHEMBL5335559 | 0.82 | GRN (0.39) | GRNSORT1 | |
| Hydrochloric Acid SCHEMBL7101089 | 0.81 | GRN (0.38) | GRNSORT1 | |
| SCHEMBL28917210 | 0.80 | CYP2D6 (0.36) | CYP2D6MEN1GAAKMT2AHDAC3 | |
| SCHEMBL6156040 | 0.79 | ECE1 (0.41) | MEN1KMT2AGRNSORT1 | |
| SCHEMBL10048032 | 0.79 | CYP2D6 (0.42) | CYP2D6MEN1GAAKMT2AHDAC3 | |
| SCHEMBL12570554 | 0.79 | CYP2D6 (0.42) | CYP2D6MEN1GAAKMT2AHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6627431-B1 | Hydrolyzing the ester using a lipase from Pseudomonas and esterase from porcine liver; use as artificial sweetener | THE NUTRASWEET COMPANY | 2003-09-30 | — | — | US | disclosed |
| EP-1140795-B1 | N-3, 3-DIMETHYLBUTYL-L-ASPARTIC ACID AND ESTERS THEREOF, THE PROCESS OF PREPARING THE SAME, AND THE PROCESS FOR PREPARING N-[N-(3,3-DIMETHYLBUTYL)-L-ALPHA-ASPARTYL)-L-PHENYLALANINE-1-METHYLESTER THEREFROM | NUTRASWEET CO (US) | 2003-09-03 | — | — | EP | disclosed |
| WO-2001085977-A2 | CHEMOENZYMATIC SYNTHESIS OF NEOTAME | THE NUTRASWEET COMPANY (US) | 2001-11-15 | — | — | WO | disclosed |
| US-6077962-A | N-3, 3-dimethylbutyl-L-aspartic acid and esters thereof, the process of preparing the same, and the process for preparing N-(N-(3,3-dimethylbutyl) -α L-aspartyl)-L- phenylalanine 1-methyl ester therefrom | THE NUTRASWEET COMPANY (US) | 2000-06-20 | — | — | US | disclosed |