Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 3/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GGT1 | P19440 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7103783 | 0.88 | CYP2D6 (0.39) | GRNSORT1TSHRMEN1GAA | |
| Hydrochloric Acid SCHEMBL7102139 | 0.87 | CYP2D6 (0.38) | GRNSORT1MEN1GAAKMT2A | |
| SCHEMBL7097493 | 0.86 | CA1 (0.33) | TSHR | |
| SCHEMBL7763255 | 0.85 | MEN1 (0.32) | TSHRMEN1GAAKMT2ASLC1A1 | |
| SCHEMBL7099887 | 0.84 | GRN (0.39) | GRNSORT1 | |
| SCHEMBL5335559 | 0.84 | GRN (0.39) | GRNSORT1 | |
| Hydrochloric Acid SCHEMBL7101089 | 0.82 | GRN (0.38) | GRNSORT1 | |
| SCHEMBL6156040 | 0.81 | ECE1 (0.41) | GRNSORT1MEN1KMT2AGGT1 | |
| SCHEMBL7097154 | 0.76 | RRM1 (0.32) | GRNSORT1 | |
| SCHEMBL11246906 | 0.76 | TSHR (0.39) | TSHRMEN1KMT2ATGFBR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6627431-B1 | Hydrolyzing the ester using a lipase from Pseudomonas and esterase from porcine liver; use as artificial sweetener | THE NUTRASWEET COMPANY | 2003-09-30 | — | — | US | disclosed |
| WO-2001085977-A2 | CHEMOENZYMATIC SYNTHESIS OF NEOTAME | THE NUTRASWEET COMPANY (US) | 2001-11-15 | — | — | WO | disclosed |