Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | FABP3 | P05413 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7103787 | 0.92 | GSK3B (0.38) | GSK3BMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL7673820 | 0.83 | MAPK8 (0.43) | GSK3BMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL5092424 | 0.77 | SMN1; SMN2 (0.46) | GSK3BMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL5089087 | 0.76 | POLB (0.50) | GSK3BMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL5089170 | 0.76 | SMN1; SMN2 (0.43) | GSK3BMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL5089453 | 0.75 | POLB (0.47) | GSK3BMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL7107228 | 0.75 | GSK3B (0.50) | GSK3BMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL7855969 | 0.75 | SCD (0.34) | GSK3BMAPTMEN1KMT2AMKNK1 | |
| SCHEMBL5099951 | 0.75 | MAPT (0.47) | GSK3BMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL5101064 | 0.75 | KMT2A (0.43) | MAPTMEN1KMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1317433-A2 | INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | CHIRON CORPORATION (US) | 2003-06-11 | — | — | EP | disclosed |
| WO-2002020495-A2 | INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | CHIRON CORPORATION (US) | 2002-03-14 | — | — | WO | disclosed |