Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 6/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.49 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9325701 | 0.97 | EPHX2 (0.60) | EPHX2TDP1NPC1RAB9AGAA | |
| SCHEMBL11345029 | 0.91 | TDP1 (0.69) | EPHX2TDP1NPC1RAB9AGAA | |
| SCHEMBL11246531 | 0.90 | TDP1 (0.52) | EPHX2TDP1NPC1RAB9AGAA | |
| SCHEMBL7108246 | 0.90 | MEN1 (0.53) | EPHX2TDP1NPC1RAB9AGAA | |
| SCHEMBL10795425 | 0.87 | TDP1 (0.51) | EPHX2TDP1NPC1RAB9AGAA | |
| SCHEMBL11319143 | 0.87 | MAPT (0.60) | EPHX2TDP1MAPTTRPV1ALDH1A1 | |
| SCHEMBL11560696 | 0.87 | EPHX2 (0.60) | EPHX2TDP1NPC1RAB9AGAA | |
| SCHEMBL9651342 | 0.87 | MEN1 (0.48) | EPHX2TDP1NPC1RAB9AGAA | |
| SCHEMBL10707659 | 0.86 | MEN1 (0.50) | EPHX2TDP1NPC1RAB9AGAA | |
| SCHEMBL11026869 | 0.86 | MEN1 (0.53) | EPHX2TDP1NPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE32418-E | INSECTICIDES | THE DOW CHEMICAL COMPANY (US) | 1987-05-12 | — | — | US | claimed |
| EP-0107214-A2 | Pharmaceutical compositions containing benzoyl-phenyl ureas with anti-tumour activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1984-05-02 | — | — | EP | claimed |
| US-4170657-A | INSECTICIDES | THE DOW CHEMICAL COMPANY (US) | 1979-10-09 | — | — | US | claimed |
| US-4139636-A | N-Phenyl-N'-benzoyl-ureas and pesticidal compositions and uses therefor | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-13 | — | — | US | claimed |
| US-4089975-A | DIPHENYL ACYLUREA DERIVATIVE | THE DOW CHEMICAL COMPANY (US) | 1978-05-16 | — | — | US | claimed |
| CN-102177905-B | 1-(4-trifluoromethoxybenzene)-3-(2,6-difluorobenzoyl) urea preparation | TONGHUA PESTICIDE CHEMICAL CO LTD | 2013-07-17 | — | — | CN | disclosed |
| CN-102177905-B | 1-(4-trifluoromethoxybenzene)-3-(2,6-difluorobenzoyl) urea preparation | TONGHUA PESTICIDE CHEMICAL CO LTD | 2013-07-17 | — | — | CN | disclosed |
| CN-102177905-A | 1-(4-trifluoromethoxybenzene)-3-(2,6-difluorobenzoyl) urea preparation | TONGHUA PESTICIDE CHEMICAL CO LTD | 2011-09-14 | — | — | CN | disclosed |
| CN-102177904-A | Compound preparation of 1-[4-(trifluoromethoxy)phenyl]-3-(2,6-difluorobenzoyl)urea and chlorantraniliprole | TONGHUA PESTICIDE CHEMICAL CO LTD | 2011-09-14 | — | — | CN | disclosed |
| CN-102177905-A | 1-(4-trifluoromethoxybenzene)-3-(2,6-difluorobenzoyl) urea preparation | TONGHUA PESTICIDE CHEMICAL CO LTD | 2011-09-14 | — | — | CN | disclosed |
| CN-102177904-A | Compound preparation of 1-[4-(trifluoromethoxy)phenyl]-3-(2,6-difluorobenzoyl)urea and chlorantraniliprole | TONGHUA PESTICIDE CHEMICAL CO LTD | 2011-09-14 | — | — | CN | disclosed |
| EP-0917822-B1 | Method to control animal ecto-parasites | SUMITOMO CHEMICAL CO (JP) | 2003-10-08 | — | — | EP | disclosed |
| EP-0368285-A2 | Improved pesticidal composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-05-16 | — | — | EP | disclosed |
| EP-0211004-A1 | USE OF ACYL UREA COMPOUNDS FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES OF WARM-BLOODED ANIMALS | RHONE-POULENC NEDERLAND B.V. (NL) | 1987-02-25 | — | — | EP | disclosed |
| EP-0193249-A2 | Benzoyl urea derivatives having ati-tumor activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1986-09-03 | — | — | EP | disclosed |
| WO-1986003941-A1 | USE OF ACYL UREA COMPOUNDS FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES OF WARM-BLOODED ANIMALS | UNION CARBIDE CORPORATION (US) | 1986-07-17 | — | — | WO | disclosed |
| EP-0107214-A2 | Pharmaceutical compositions containing benzoyl-phenyl ureas with anti-tumour activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1984-05-02 | — | — | EP | disclosed |
| US-4438110-A | 1-(MONO-SUBSTITUTED PHENYL)-3-BENZOYL UREA AND A PHOSPHOROUS CONTAINING COMPOUND | UNION CARBIDE CORPORATION (US) | 1984-03-20 | — | — | US | disclosed |
| US-4431667-A | Imino ethers useful for controlling insect and arachnoid pests | THE UPJOHN COMPANY (US) | 1984-02-14 | — | — | US | disclosed |
| US-4089975-A | DIPHENYL ACYLUREA DERIVATIVE | THE DOW CHEMICAL COMPANY (US) | 1978-05-16 | — | — | US | disclosed |