Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.49 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.49 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7209594 | 0.87 | SLC2A1 (0.62) | SLC2A1MEN1GFERKMT2AKCNH2 | |
| SCHEMBL5376778 | 0.85 | SLC2A1 (0.57) | SLC2A1MEN1GFERKMT2AKCNH2 | |
| SCHEMBL10069522 | 0.81 | SLC2A1 (0.66) | SLC2A1MEN1GFERKMT2AKCNH2 | |
| Hydrochloric Acid SCHEMBL5376732 | 0.80 | SLC2A1 (0.61) | SLC2A1MEN1GFERKMT2AKCNH2 | |
| Hydrochloric Acid SCHEMBL5379315 | 0.78 | SLC2A1 (0.59) | SLC2A1MEN1GFERKMT2AKCNH2 | |
| SCHEMBL6622297 | 0.78 | SLC2A1 (0.50) | SLC2A1BCHE | |
| SCHEMBL8221201 | 0.78 | SLC2A1 (0.54) | SLC2A1MEN1GFERKMT2AKCNH2 | |
| SCHEMBL5669372 | 0.77 | MARS1 (0.64) | SLC2A1 | |
| SCHEMBL10069523 | 0.77 | SLC2A1 (0.60) | SLC2A1MEN1GFERKMT2AKCNH2 | |
| SCHEMBL8215088 | 0.77 | SLC2A1 (1.00) | SLC2A1MEN1GFERKMT2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003500395-A | — | — | 2003-01-07 | — | — | JP | claimed |
| WO-2000071522-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS METHIONYL T-RNA SYNTHETASE INHIBITORS | SMITHKLINE BEECHAM PLC (GB) | 2000-11-30 | — | — | WO | claimed |
| WO-2000071522-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS METHIONYL T-RNA SYNTHETASE INHIBITORS | SMITHKLINE BEECHAM PLC (GB) | 2000-11-30 | — | — | WO | disclosed |