SCHEMBL7104096

SCHEMBL7104096

O=C(COc1ccccc1)c1ccc(O)cc1

nearest known ligand 0.82

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.61
NPC1 O15118 2/20 0.61
RAB9A P51151 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
LMNA P02545 2/20 0.59
ALOX15 P16050 1/20 0.57
MAPK1 P28482 1/20 0.56
CASP3 P42574 1/20 0.56
SENP7 Q9BQF6 1/20 0.56
SENP6 Q9GZR1 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
ALDH1A1 P00352 1/20 0.56
KMT2A Q03164 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9787020 0.93 NPC1 (0.66) MAPTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL1068092 0.88 MAPT (0.69) MAPTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL11572765 0.87 MAPT (0.76) MAPTNPC1RAB9ASMN1; SMN2LMNA
Hydrochloric Acid SCHEMBL8136104 0.86 MAPT (0.67) MAPTNPC1RAB9ASMN1; SMN2LMNA
Methane SCHEMBL28765047 0.86 MAPT (0.67) MAPTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL9787024 0.85 MAPT (0.79) MAPTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL10486772 0.85 MAPT (0.66) MAPTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL9786970 0.84 MAPT (0.74) MAPTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL8761648 0.84 MAPT (0.59) MAPTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL20491505 0.84 LMNA (0.77) MAPTNPC1RAB9ASMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022135617-A1 NOVEL NAMPT ENZYME AGONIST AND PREPARATION AND USE THEREOF 清华大学 2022-06-30 WO disclosed
EP-0744464-B1 Liquid peracid precursor colloidal dispersions: liquid crystals CLOROX CO (US) 2003-01-22 EP disclosed
EP-0744463-B1 Liquid peracid precursor colloidal dispersions: oil-core vesicles CLOROX CO (US) 2003-01-22 EP disclosed
EP-0744462-B1 Liquid peracid precursor colloidal dispersions: microemulsions CLOROX CO (US) 2002-08-07 EP disclosed
US-5977044-A PARTITIONED CONTAINER PETERSON DAVID (US) 1999-11-02 US disclosed
US-5954998-A BLEACH DELIVERY ACTIVATORS THE CLOROX COMPANY (US) 1999-09-21 US disclosed
US-5877137-A DIVIDED CONTAINER FOR SUPPLYING BLEACH AND EMULSIFIER THE CLOROX COMPANY (US) 1999-03-02 US disclosed
US-5877136-A Liquid peracid precursor colloidal dispersions: Liquid crystals THE CLOROX COMPANY (US) 1999-03-02 US disclosed
US-5792385-A STORAGE STABLE THE CLOROX COMPANY (US) 1998-08-11 US disclosed
US-5776877-A CONTAINER THE CLOROX COMPANY (US) 1998-07-07 US disclosed
US-5681805-A STABLE LIQUID BLEACH, CLEANING COMPOUND THE CLOROX COMPANY (US) 1997-10-28 US disclosed
EP-0744463-A2 Liquid peracid precursor colloidal dispersions: oil-core vesicles The Clorox Company (US) 1996-11-27 EP disclosed
EP-0744462-A2 Liquid peracid precursor colloidal dispersions: microemulsions The Clorox Company (US) 1996-11-27 EP disclosed
EP-0744464-A2 Liquid peracid precursor colloidal dispersions: liquid crystals The Clorox Company (US) 1996-11-27 EP disclosed
EP-0744465-A2 Liquid peracid precursor colloidal dispersions: Macroemulsions The Clorox Company (US) 1996-11-27 EP disclosed