Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1F | O60840 | 7/20 | 0.60 |
| ▸ | CACNA1D | Q01668 | 7/20 | 0.60 |
| ▸ | CACNA1S | Q13698 | 7/20 | 0.60 |
| ▸ | CACNA1C | Q13936 | 7/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.57 |
| ▸ | THPO | P40225 | 2/20 | 0.57 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7377596 | 1.00 | CACNA1F (0.60) | CACNA1FCACNA1DCACNA1SCACNA1CMEN1 | |
| SCHEMBL9387549 | 0.97 | CACNA1F (0.64) | CACNA1FCACNA1DCACNA1SCACNA1CMEN1 | |
| Hydrochloric Acid SCHEMBL7758688 | 0.96 | CACNA1F (0.62) | CACNA1FCACNA1DCACNA1SCACNA1CMEN1 | |
| SCHEMBL7379582 | 0.94 | MEN1 (0.65) | CACNA1FCACNA1DCACNA1SCACNA1CMEN1 | |
| SCHEMBL10666388 | 0.94 | CACNA1F (0.68) | CACNA1FCACNA1DCACNA1SCACNA1CMEN1 | |
| SCHEMBL10668484 | 0.92 | CACNA1F (0.57) | CACNA1FCACNA1DCACNA1SCACNA1CMEN1 | |
| SCHEMBL7110929 | 0.91 | CACNA1F (0.59) | CACNA1FCACNA1DCACNA1SCACNA1CMEN1 | |
| SCHEMBL7110931 | 0.91 | CACNA1F (0.59) | CACNA1FCACNA1DCACNA1SCACNA1CMEN1 | |
| Hydrochloric Acid SCHEMBL7376947 | 0.90 | CACNA1F (0.58) | CACNA1FCACNA1DCACNA1SCACNA1CMEN1 | |
| SCHEMBL7375431 | 0.89 | MEN1 (0.56) | CACNA1FCACNA1DCACNA1SCACNA1CMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846759-B1 | GENE ENCODING PROTEIN HAVING ASYMMETRIC HYDROLASE ACTIVITY ON 4-SUBSTITUTED-1,4-DIHYDROPYRIDINE DERIVATIVES AND EXPRESSION PRODUCT OF THE SAME | MERCIAN CORP (JP) | 2003-10-01 | — | — | EP | disclosed |
| EP-0657429-B1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE 1,4-DIHYDROPYRIDINE COMPOUNDS | MERCIAN CORP (JP) | 2001-04-11 | — | — | EP | disclosed |
| US-5684580-A | Hydrocarbon analysis and control by raman spectroscopy | ASHLAND INC. (US) | 1997-11-04 | — | — | US | disclosed |
| US-5635395-A | Optically active 1,4-dihydropyridine compounds and the microbial process for the stereoselection thereof | MERCIAN CORPORATION (JP) | 1997-06-03 | — | — | US | disclosed |
| EP-0657429-A1 | OPTICALLY ACTIVE 1,4-DIHYDROPYRIDINE COMPOUND AND PROCESS FOR PRODUCING THE SAME | MERCIAN CORPORATION (JP) | 1995-06-14 | — | — | EP | disclosed |