Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.65 |
| ▸ | THPO | P40225 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.61 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.61 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9387549 | 0.98 | CACNA1F (0.64) | MEN1KMT2AMAPTCYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL7758688 | 0.97 | CACNA1F (0.62) | MEN1KMT2AMAPTCYP1A2CYP3A4 | |
| SCHEMBL10666388 | 0.95 | CACNA1F (0.68) | MEN1KMT2AMAPTCYP1A2CYP3A4 | |
| SCHEMBL7104237 | 0.94 | CACNA1F (0.60) | MEN1KMT2AMAPTCYP1A2CYP3A4 | |
| SCHEMBL7377596 | 0.94 | CACNA1F (0.60) | MEN1KMT2AMAPTCYP1A2CYP3A4 | |
| SCHEMBL10668484 | 0.92 | CACNA1F (0.57) | MEN1KMT2AMAPTCYP1A2CYP3A4 | |
| SCHEMBL7110931 | 0.92 | CACNA1F (0.59) | MEN1KMT2AMAPTCYP1A2CYP3A4 | |
| SCHEMBL7110929 | 0.92 | CACNA1F (0.59) | MEN1KMT2AMAPTCYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL7376947 | 0.91 | CACNA1F (0.58) | MEN1KMT2AMAPTCYP1A2CYP3A4 | |
| SCHEMBL9672319 | 0.91 | MEN1 (0.70) | MEN1KMT2AMAPTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0370821-B1 | 1,4-dihydropyridine derivatives | TAISHO PHARMACEUTICAL CO LTD (JP) | 1994-09-14 | — | — | EP | disclosed |
| US-5047543-A | Hypertensive and antiischemic agents | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1991-09-10 | — | — | US | disclosed |
| EP-0370821-A2 | 1,4-dihydropyridine derivatives | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1990-05-30 | — | — | EP | disclosed |
| US-4727066-A | CARDIOVASCULAR DISORDERS | CERMOL S.A. (CH) | 1988-02-23 | — | — | US | disclosed |
| US-4656181-A | CARDIOTONIC AGENTS | CERMOL S.A. (CH) | 1987-04-07 | — | — | US | disclosed |