Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 6/20 | 0.54 |
| ▸ | PARP15 | Q460N3 | 5/20 | 0.54 |
| ▸ | ACACB | O00763 | 6/20 | 0.52 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.50 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3498383 | 0.99 | PARP10 (0.53) | PARP10PARP15ACACBADAM17PARP2 | |
| Hydrochloric Acid SCHEMBL3498380 | 0.99 | PARP10 (0.53) | PARP10PARP15ACACBADAM17PARP2 | |
| Hydrochloric Acid SCHEMBL3500467 | 0.92 | ACACB (0.57) | PARP10PARP15ACACBPARP2 | |
| Hydrochloric Acid SCHEMBL3500469 | 0.92 | ACACB (0.57) | PARP10PARP15ACACBPARP2 | |
| Hydrochloric Acid SCHEMBL7492814 | 0.88 | PARP10 (0.52) | PARP10PARP15ACACBADAM17PARP2 | |
| SCHEMBL2923430 | 0.86 | PARP10 (0.58) | PARP10PARP15ACACBPARP2FFAR1 | |
| SCHEMBL2923427 | 0.86 | PARP10 (0.58) | PARP10PARP15ACACBPARP2FFAR1 | |
| SCHEMBL7538892 | 0.81 | PARP15 (0.45) | PARP10PARP15ACACBADAM17 | |
| SCHEMBL7327020 | 0.81 | ACACB (0.47) | ACACBPTGS2 | |
| SCHEMBL7327023 | 0.81 | ACACB (0.47) | ACACBPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991619-B1 | INHIBITORS OF ALPHA 4-BETA 1 MEDIATED CELL ADHESION | TANABE SEIYAKU CO (JP) | 2003-09-10 | — | — | EP | disclosed |
| US-20030130349-A1 | Inhibitors of alpha 4beta1 mediated cell adhesion | TANABE SEIYAKU CO., LTD. | 2003-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130349-A1 | Inhibitors of alpha 4beta1 mediated cell adhesion | VCAM1, ICAM1, ITGB1 | PARP10 1993/4885PARP15 1528/4885ACACB 932/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.