SCHEMBL7104561

SCHEMBL7104561

Clc1cc(Cl)cc(SCc2ccccc2)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 5/20 0.49
MAOB P27338 5/20 0.49
SOD1 P00441 1/20 0.46
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
ALDH1A1 P00352 2/20 0.44
POLB P06746 1/20 0.44
HSD17B10 Q99714 1/20 0.44
DAO P14920 1/20 0.44
SLC6A4 P31645 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
L3MBTL1 Q9Y468 2/20 0.41
MAPT P10636 1/20 0.41
CYP3A4 P08684 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
ALOX12 P18054 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28101221 0.84 MAOB (0.50) MAOAMAOBMEN1KMT2AALDH1A1
SCHEMBL28283253 0.81 MEN1 (0.66) MAOAMAOBMEN1KMT2ANPC1
SCHEMBL17397997 0.80 POLB (0.49) MAOAMAOBKMT2ANPC1RAB9A
Methyl Alcohol SCHEMBL27517044 0.80 TDP1 (0.50) MAOAMAOBALDH1A1DAOSLC6A4
SCHEMBL1828030 0.80 MAOA (0.42) MAOAMAOBMEN1KMT2ANPC1
SCHEMBL22865221 0.79 MAOA (0.45) MAOAMAOBMEN1KMT2ANPC1
SCHEMBL3938204 0.78 DAO (0.51) MEN1KMT2ANPC1RAB9ADAO
SCHEMBL5335799 0.78 NPC1 (0.43) MAOAMAOBMEN1KMT2ANPC1
SCHEMBL7808681 0.77 HAO1 (0.50) MAOAMAOBMEN1KMT2ANPC1
SCHEMBL332623 0.77 MAOA (0.63) MAOAMAOBMEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119462447-A Method for synthesizing aryl thioether compound 常州大学 2025-02-18 CN disclosed
EP-1044965-B1 PROCESS FOR THE PREPARATION OF AROMATIC SULFUR COMPOUNDS NIPPON FINECHEMICAL CO LTD (JP) 2003-10-01 EP disclosed
US-6444853-B1 FROM AROMATIC THIOETHER NIPPON FINECHEMICAL CO., LTD. (JP) 2002-09-03 US disclosed
US-6376716-B1 REACTING AN AROMATIC THIOETHER WITH LEWIS ACIDS; FORMING AROMATIC MERCAPTAN NIPPON FINECHEMICAL CO., LTD. (JP) 2002-04-23 US disclosed
EP-1044965-A1 PROCESS FOR THE PREPARATION OF AROMATIC SULFUR COMPOUNDS Nippon Finechemical Co., Ltd. (JP) 2000-10-18 EP disclosed