Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.49 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.49 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7101436 | 0.85 | CYSLTR2 (0.56) | CYSLTR2CYSLTR1RAB9AKCNH2KDM1A | |
| SCHEMBL7103500 | 0.80 | ESR2 (0.53) | CYSLTR2CYSLTR1CYP2D6 | |
| SCHEMBL11611381 | 0.79 | AKR1C3 (0.46) | AKR1C3AKR1C1 | |
| SCHEMBL8413386 | 0.78 | CYSLTR2 (0.49) | CYSLTR2CYSLTR1RAB9AKCNH2KDM1A | |
| SCHEMBL7098576 | 0.77 | MAOB (0.50) | CYSLTR2CYSLTR1KCNH2KDM1AFFAR1 | |
| SCHEMBL29932805 | 0.77 | MAOB (0.50) | CYSLTR2CYSLTR1KCNH2KDM1AFFAR1 | |
| SCHEMBL12209855 | 0.75 | AKR1C3 (0.56) | CYSLTR2CYSLTR1AKR1C3AKR1C1 | |
| SCHEMBL19322267 | 0.74 | KDM1A (0.57) | MMP3RAB9AKCNH2SCN3AKDM1A | |
| SCHEMBL3970721 | 0.74 | KDM1A (0.57) | MMP3RAB9AKCNH2SCN3AKDM1A | |
| SCHEMBL22549670 | 0.71 | AKR1C3 (0.49) | CYSLTR2CYSLTR1KCNH2AKR1C3AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003095441-A1 | INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME | PFIZER INC. (US) | 2003-11-20 | — | — | WO | disclosed |