Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.56 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.56 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8413386 | 0.93 | CYSLTR2 (0.49) | CYSLTR2CYSLTR1MRGPRX4MAOBKCNH2 | |
| SCHEMBL29932805 | 0.87 | MAOB (0.50) | CYSLTR2CYSLTR1MRGPRX4MAOBKCNH2 | |
| SCHEMBL7098576 | 0.87 | MAOB (0.50) | CYSLTR2CYSLTR1MRGPRX4MAOBKCNH2 | |
| SCHEMBL7104596 | 0.85 | CYSLTR2 (0.49) | CYSLTR2CYSLTR1KCNH2KDM1ARAB9A | |
| SCHEMBL7097124 | 0.82 | APP (0.59) | KDM4ERAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7101427 | 0.81 | CYSLTR2 (0.51) | CYSLTR2CYSLTR1MRGPRX4MAOBKCNH2 | |
| SCHEMBL27546384 | 0.79 | RAB9A (0.56) | CYSLTR2CYSLTR1MRGPRX4MAOBKCNH2 | |
| SCHEMBL7103500 | 0.79 | ESR2 (0.53) | CYSLTR2CYSLTR1 | |
| SCHEMBL10272647 | 0.78 | MRGPRX4 (0.64) | MRGPRX4MAOBKCNH2KDM1AMAOA | |
| SCHEMBL23364576 | 0.77 | CYSLTR2 (0.53) | CYSLTR2CYSLTR1MRGPRX4MAOBKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003095441-A1 | INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME | PFIZER INC. (US) | 2003-11-20 | — | — | WO | disclosed |