Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7103970 | 0.96 | S1PR1 (0.36) | SPHK1S1PR1S1PR5DGAT1S1PR3 | |
| SCHEMBL7105430 | 0.92 | S1PR1 (0.38) | S1PR1S1PR5DGAT1S1PR3 | |
| SCHEMBL7106833 | 0.87 | S1PR1 (0.39) | S1PR1S1PR5DGAT1 | |
| SCHEMBL15668804 | 0.84 | S1PR1 (0.38) | S1PR1S1PR5DGAT1 | |
| SCHEMBL7109460 | 0.84 | GCGR (0.38) | NPC1RAB9A | |
| SCHEMBL7109432 | 0.82 | KDM4E (0.41) | RAB9A | |
| SCHEMBL7111520 | 0.82 | TLR8 (0.38) | NPC1RAB9A | |
| SCHEMBL7110767 | 0.82 | KDM4E (0.38) | RAB9A | |
| SCHEMBL7111531 | 0.82 | KDM4E (0.40) | RAB9A | |
| SCHEMBL7108900 | 0.82 | KDM4E (0.40) | RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1053263-B1 | CATALYST SYSTEM | BASELL POLYOLEFINE GMBH (DE) | 2003-10-01 | — | — | EP | claimed |