Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 7/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 4/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.31 |
| ▸ | NOS3 | P29474 | 2/20 | 0.31 |
| ▸ | NOS1 | P29475 | 2/20 | 0.31 |
| ▸ | NOS2 | P35228 | 2/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7104714 | 0.96 | SPHK1 (0.36) | S1PR1S1PR5DGAT1S1PR3SPHK1 | |
| SCHEMBL7105430 | 0.94 | S1PR1 (0.38) | S1PR1S1PR5DGAT1NOTUMS1PR3 | |
| SCHEMBL7106833 | 0.89 | S1PR1 (0.39) | S1PR1S1PR5DGAT1NOTUMNOS3 | |
| SCHEMBL15668804 | 0.86 | S1PR1 (0.38) | S1PR1S1PR5DGAT1NOTUM | |
| SCHEMBL7109744 | 0.83 | SMN1; SMN2 (0.34) | — | |
| SCHEMBL7106920 | 0.82 | HSD11B1 (0.38) | S1PR1DGAT1 | |
| SCHEMBL7105395 | 0.81 | TLR8 (0.34) | — | |
| SCHEMBL7109565 | 0.81 | HSD11B1 (0.35) | S1PR1 | |
| SCHEMBL7110309 | 0.79 | UCHL3 (0.37) | DGAT1 | |
| SCHEMBL7105422 | 0.79 | NPC1 (0.35) | S1PR1S1PR5DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1053263-B1 | CATALYST SYSTEM | BASELL POLYOLEFINE GMBH (DE) | 2003-10-01 | — | — | EP | claimed |