SCHEMBL7104955

SCHEMBL7104955

OC[C@H]1O[C@H](OC[C@@H](O)[C@@H](O)[C@H](O)c2cnc3cc(Cl)c(Cl)cc3n2)[C@H](O)[C@@H](O)[C@@H]1O

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CD209 Q9NNX6 3/20 0.39
KDM4E B2RXH2 1/20 0.37
GMNN O75496 1/20 0.37
LMNA P02545 1/20 0.37
MAPT P10636 1/20 0.37
BLM P54132 1/20 0.37
PMP22 Q01453 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
TSHR P16473 1/20 0.37
NFKB1 P19838 1/20 0.37
STAT6 P42226 1/20 0.37
HIF1A Q16665 1/20 0.37
HDAC6 Q9UBN7 1/20 0.35
SLC5A2 P31639 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7105467 0.86 CD209 (0.42) CD209
SCHEMBL7103572 0.86 CD209 (0.42) CD209
SCHEMBL1782151 0.73 GAA (0.50) MAPT
SCHEMBL21245905 0.73 GAA (0.50) MAPT
SCHEMBL7153515 0.73 GAA (0.50) MAPT
SCHEMBL12798033 0.73 GAA (0.50) MAPT
SCHEMBL1782020 0.73 GAA (0.50) MAPT
SCHEMBL21245904 0.73 GAA (0.50) MAPT
SCHEMBL12604144 0.73 GAA (0.50) MAPT
SCHEMBL12206047 0.70 CETP (0.48) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030207886-A1 Preparation containing quinoxaline derivatives MERCK PATENT GMBH (DE) 2003-11-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030207886-A1 Preparation containing quinoxaline derivatives CUTA, XPA, NQO2 CD209 4472/4885KDM4E 467/4885GMNN 2372/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.