SCHEMBL7104978

SCHEMBL7104978

CCCC(N)C1CCCCC1

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.46
EPHX1 P07099 2/20 0.41
DPP4 P27487 1/20 0.39
TP53 P04637 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
KDM4E B2RXH2 1/20 0.37
GMNN O75496 1/20 0.37
LMNA P02545 1/20 0.37
MAPT P10636 1/20 0.37
BLM P54132 1/20 0.37
PMP22 Q01453 1/20 0.37
CYP1A2 P05177 1/20 0.34
SIGMAR1 Q99720 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20319041 1.00 SHBG (0.46) SHBGEPHX1DPP4TP53SMN1; SMN2
SCHEMBL30142421 1.00 SHBG (0.46) SHBGEPHX1DPP4TP53SMN1; SMN2
Hydrochloric Acid SCHEMBL9196277 0.98 SHBG (0.44) SHBGEPHX1DPP4TP53SMN1; SMN2
SCHEMBL19578580 0.98 SHBG (0.42) SHBGEPHX1DPP4TP53SMN1; SMN2
SCHEMBL5384279 0.87
SCHEMBL8738301 0.87
SCHEMBL5806546 0.86 SHBG (0.43) SHBGEPHX1DPP4TP53SMN1; SMN2
Hydrochloric Acid SCHEMBL6082121 0.85
Hydrochloric Acid SCHEMBL22321784 0.85
SCHEMBL2781157 0.85 EPHX1 (0.48) SHBGEPHX1DPP4TP53SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101195711-B Polyamic acid composition and alignment film prepared from same DALI POLYMER CO LTD 2012-07-04 CN claimed
CN-101195711-A Polyamic acid composition and alignment film prepared from same DALI POLYMER CO LTD (CN) 2008-06-11 CN claimed
US-12152014-B2 Therapeutic compounds and compositions eXlthera Pharmaceuticals, Inc. (US) 2024-11-26 US disclosed
US-20240059670-A1 THERAPEUTIC COMPOUNDS AND COMPOSITIONS Cadrenal Therapeutics, Inc. 2024-02-22 US disclosed
US-11691962-B2 Therapeutic compounds and compositions EXITHERA PHARMACEUTICALS, INC. (US) 2023-07-04 US disclosed
CN-111868842-B Conductive paste with stable viscosity over time 株式会社则武 2021-11-19 CN disclosed
US-20210188812-A1 THERAPEUTIC COMPOUNDS AND COMPOSITIONS Cadrenal Therapeutics, Inc. 2021-06-24 US disclosed
CN-111868842-A Conductive paste with stable viscosity over time 株式会社则武 2020-10-30 CN disclosed
US-20190315711-A1 THERAPEUTIC COMPOUNDS AND COMPOSITIONS Cadrenal Therapeutics, Inc. 2019-10-17 US disclosed
CN-101195711-B Polyamic acid composition and alignment film prepared from same DALI POLYMER CO LTD 2012-07-04 CN disclosed
EP-1385870-B1 PEPTIDES AS NS3-SERINE PROTEASE INHIBITORS OF HEPATITIS C VIRUS SCHERING CORP (US) 2010-03-17 EP disclosed
US-5686066-A Polyaspartic acid Zwitterionic derivatives, preparation processes thereof, hair-treating compositions and cosmetic compositions MITSUI TOATSU CHEMICALS, INC. (JP) 1997-11-11 US disclosed
EP-0769532-A1 Naphtholactamimide fluorescent dyes Ciba SC Holding AG (CH) 1997-04-23 EP disclosed
EP-0767191-A2 Polymer, preparation process thereof, hairtreating compositions and cosmetic compositions MITSUI TOATSU CHEMICALS, INC. (JP) 1997-04-09 EP disclosed
CN-1031059-C 7-oxabicycloheptyl substituted heterocyclic amide prostaglandin analogs useful in treatment of thrombotic and vasospastic disease SQUIBB & SONS INC (US) 1996-02-21 CN disclosed
US-5420283-A Resolution of (R)-2-benzylsuccinic acid 4-[4-(N-t-butoxycarbonylmethylamino)-piperidine] amide PFIZER INC. (US) 1995-05-30 US disclosed
EP-0391652-B1 Interphenylène 7-oxabicycloheptyl substituted heterocyclic amide prostaglandin analogs useful in the treatment of thrombotic and vasopastic disease SQUIBB & SONS INC (US) 1995-03-15 EP disclosed
EP-0391652-A1 Interphenylène 7-oxabicycloheptyl substituted heterocyclic amide prostaglandin analogs useful in the treatment of thrombotic and vasopastic disease E.R. SQUIBB & SONS, INC. (US) 1990-10-10 EP disclosed
CN-1043716-A Be used for the treatment of the heterocycleamide prostaglandin analogue that thrombus and angiospastic 7-oxabicyclo heptyl replace SQUIBB & SONS INC (US) 1990-07-11 CN disclosed
US-4243681-A VASODILATION, ANTISPASMODIC AGENTS; ANTICOAGULANTS MEAD JOHNSON & COMPANY (US) 1981-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240059670-A1 THERAPEUTIC COMPOUNDS AND COMPOSITIONS KLK5, KLK2, KLKB1 SHBG 660/4885EPHX1 818/4885DPP4 578/4885
US-20210188812-A1 THERAPEUTIC COMPOUNDS AND COMPOSITIONS KLK5, KLK2, KLKB1 SHBG 660/4885EPHX1 818/4885DPP4 578/4885
US-12152014-B2 Therapeutic compounds and compositions KLK5, KLK2, KLKB1 SHBG 660/4885EPHX1 818/4885DPP4 578/4885
US-11691962-B2 Therapeutic compounds and compositions KLK5, KLK2, KLKB1 SHBG 660/4885EPHX1 818/4885DPP4 578/4885
US-20190315711-A1 THERAPEUTIC COMPOUNDS AND COMPOSITIONS KLK5, KLK2, KLKB1 SHBG 660/4885EPHX1 818/4885DPP4 578/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.