⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Malonodihydroxamic Acid SCHEMBL3246123 | 0.78 | — | — | |
| SCHEMBL1401066 | 0.76 | MGAM (0.45) | — | |
| SCHEMBL8249763 | 0.75 | — | — | |
| SCHEMBL2128645 | 0.73 | MGAM (0.56) | — | |
| SCHEMBL1608 | 0.73 | — | — | |
| SCHEMBL10389469 | 0.73 | MGAM (0.56) | — | |
| SCHEMBL260075 | 0.73 | — | — | |
| SCHEMBL11800107 | 0.72 | HDAC8 (0.47) | — | |
| SCHEMBL7094622 | 0.71 | — | — | |
| SCHEMBL11462728 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0125782-B1 | PROCESS FOR PREPARING 3-HYDROXY-5-METHYLISOXAZOLE | SANKYO COMPANY LIMITED (JP) | 1988-07-27 | — | — | EP | claimed |
| US-4634774-A | DIKETENE AND HYDROXYLAMINE | SANKYO COMPANY LIMITED (JP) | 1987-01-06 | — | — | US | claimed |
| EP-0125782-A1 | Process for preparing 3-hydroxy-5-methylisoxazole | SANKYO COMPANY LIMITED (JP) | 1984-11-21 | — | — | EP | claimed |
| JP-59190977-A | — | — | None | — | — | JP | disclosed |
| CN-117946022-A | Synthesis method of hymexazol | 青岛锐丰源化工有限公司 | 2024-04-30 | — | — | CN | disclosed |
| US-20230330189-A1 | ACYLATED GLP-1 DERIVATIVE | Sciwind Biosciences Co., Ltd. (CN) | 2023-10-19 | — | — | US | disclosed |
| US-20230295260-A1 | GLP RECEPTOR AGONISTS | HEPTARES THERAPEUTICS LIMITED (GB) | 2023-09-21 | — | — | US | disclosed |
| CN-112876374-A | Method and device for recovering excess materials of acetoacetyl arylamine alcohol process mother liquor | 青岛海湾精细化工有限公司 | 2021-06-01 | — | — | CN | disclosed |
| WO-2017172979-A1 | SUBSTITUTED QUINAZOLINE COMPOUNDS AND METHODS OF USE | ARAXES PHARMA LLC (US) | 2017-10-05 | — | — | WO | disclosed |
| US-20170247376-A1 | METHODS AND COMPOSITIONS FOR INHIBITION OF RAS | ARAXES PHARMA LLC (US) | 2017-08-31 | — | — | US | disclosed |
| WO-2017015562-A1 | SUBSTITUTED QUINAZOLINE COMPOUNDS AND THEIR USE AS INHIBITORS OF G12C MUTANT KRAS, HRAS AND/OR NRAS PROTEINS | ARAXES PHARMA LLC (US) | 2017-01-26 | — | — | WO | disclosed |
| EP-0051987-A1 | Bleach activator compositions, preparation thereof and use in granular detergent compositions | THE PROCTER & GAMBLE COMPANY (US) | 1982-05-19 | — | — | EP | disclosed |
| EP-0018678-B1 | BLEACH PRODUCTS | UNILEVER N.V. (NL) | 1982-04-07 | — | — | EP | disclosed |
| US-4321157-A | SILICA OR SILICATE, ORGANIC PEROXY ACID BLEACH PRECURSOR, ALIPHATIC ALCOHOL-ALKYLENE OXIDE CONDENSATE NONIONIC SURFACTANT | THE PROCTER & GAMBLE COMPANY (US) | 1982-03-23 | — | — | US | disclosed |
| EP-0028432-A1 | Granular laundry compositions | THE PROCTER & GAMBLE COMPANY (US) | 1981-05-13 | — | — | EP | disclosed |
| US-4248928-A | TETRAACETYL AKYLENEDIAMINES OR TETRAACETYL GLYCOURIL PEROXY BLEACH PRECURSOR | THE PROCTER & GAMBLE COMPANY (US) | 1981-02-03 | — | — | US | disclosed |
| EP-0018678-A1 | Bleach products | UNILEVER N.V. (NL) | 1980-11-12 | — | — | EP | disclosed |
| US-4179390-A | Laundry additive product | THE PROCTER & GAMBLE COMPANY (US) | 1979-12-18 | — | — | US | disclosed |
| US-4026798-A | PROLONGING USE | FMC CORPORATION (US) | 1977-05-31 | — | — | US | disclosed |
| US-4013575-A | Dry cleaning with peracids | FMC CORPORATION (US) | 1977-03-22 | — | — | US | disclosed |