SCHEMBL7105328

SCHEMBL7105328

C=CC(=O)NNC(=O)OCC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
GAA P10253 3/20 0.42
MGAM O43451 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
ALDH1A1 P00352 4/20 0.38
TSHR P16473 4/20 0.38
MAPK1 P28482 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
ZDHHC20 Q5W0Z9 1/20 0.37
ZDHHC2 Q9UIJ5 1/20 0.37
MIF P14174 1/20 0.37
HSD17B10 Q99714 1/20 0.36
HPGD P15428 1/20 0.35
CYP1A2 P05177 2/20 0.35
CYP2D6 P10635 1/20 0.35
HIF1A Q16665 1/20 0.35
ALOX15 P16050 1/20 0.34
SOAT1 P35610 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL355253 0.82 GAA (0.55) LMNASMN1; SMN2GAAMGAMSI
SCHEMBL93928 0.81 GAA (0.41) LMNAGAAMGAMSIMGAM2
SCHEMBL10896390 0.80 GAA (0.45) SMN1; SMN2GAAMGAMSIMGAM2
SCHEMBL8755750 0.79 GAA (0.39) LMNAGAAMGAMSIMGAM2
SCHEMBL27963209 0.79 GAA (0.39) LMNAGAAMGAMSIMGAM2
SCHEMBL15614528 0.77
SCHEMBL11005965 0.76 GAA (0.37) LMNASMN1; SMN2GAAMGAMSI
SCHEMBL11651480 0.75 LMNA (0.48) LMNASMN1; SMN2GAAMGAMSI
SCHEMBL28604705 0.75 LMNA (0.48) LMNASMN1; SMN2GAAMGAMSI
SCHEMBL154280 0.75 GAA (0.53) LMNASMN1; SMN2GAAMGAMSI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4223841-A2 POLYAMIDE COMPOSITIONS FOR SEALANTS AND HIGH SOLIDS PAINTS Elementis Specialties, Inc. (US) 2023-08-09 EP claimed
EP-3328938-B1 POLYAMIDE COMPOSITIONS FOR SEALANTS AND HIGH SOLIDS PAINTS ELEMENTIS SPECIALTIES INC (US) 2023-05-17 EP claimed
US-20170029565-A1 POLYAMIDE COMPOSITIONS FOR SEALANTS AND HIGH SOLIDS PAINTS ELEMENTIS SPECIALTIES, INC. (US) 2017-02-02 US claimed
EP-4223841-A2 POLYAMIDE COMPOSITIONS FOR SEALANTS AND HIGH SOLIDS PAINTS Elementis Specialties, Inc. (US) 2023-08-09 EP disclosed
EP-3328938-B1 POLYAMIDE COMPOSITIONS FOR SEALANTS AND HIGH SOLIDS PAINTS ELEMENTIS SPECIALTIES INC (US) 2023-05-17 EP disclosed
CN-109689712-B Thickening anionic copolymers 可泰克斯公司 2022-01-04 CN disclosed
US-10894900-B2 Polyamide compositions for sealants and high solids paints ELEMENTIS SPECIALTIES, INC. (US) 2021-01-19 US disclosed
US-20200277509-A1 POLYAMIDE COMPOSITIONS FOR SEALANTS AND HIGH SOLIDS PAINTS ELEMENTIS SPECIALTIES, INC. (US) 2020-09-03 US disclosed
US-10696862-B2 Polyamide compositions for sealants and high solids paints ELEMENTIS SPECIALTIES, INC. (US) 2020-06-30 US disclosed
EP-3328938-A1 POLYAMIDE COMPOSITIONS FOR SEALANTS AND HIGH SOLIDS PAINTS Elementis Specialties, Inc. (US) 2018-06-06 EP disclosed
WO-2017023759-A1 POLYAMIDE COMPOSITIONS FOR SEALANTS AND HIGH SOLIDS PAINTS ELEMENTIS SPECIALTIES, INC. (US) 2017-02-09 WO disclosed
US-4652470-A SILICA IN BASECOAT PPG INDUSTRIES, INC. (US) 1987-03-24 US disclosed
US-4620993-A Color plus clear coating system utilizing organo-modified clay in combination with organic polymer microparticles PPG INDUSTRIES, INC. (US) 1986-11-04 US disclosed
US-4620994-A Color plus clear coating system utilizing organo-modified clay PPG INDUSTRIES, INC. (US) 1986-11-04 US disclosed
US-4558075-A CROSSLINKABLE RESIN BINDER, SOLVENT SYSTEM, AND CLAY DISPERSED THEREIN PPG INDUSTRIES, INC. (US) 1985-12-10 US disclosed
US-4526910-A Film forming binder comprising crosslinkable resin, microparticles dispersed therein, solvent PPG INDUSTRIES, INC. (US) 1985-07-02 US disclosed
US-4522958-A High-solids coating composition for improved rheology control containing chemically modified inorganic microparticles PPG INDUSTRIES, INC. (US) 1985-06-11 US disclosed
EP-0139187-A1 Color plus clear coating system utilizing inorganic microparticles PPG INDUSTRIES, INC. (US) 1985-05-02 EP disclosed
US-4299743-A Sulfonate-containing polymer PPG INDUSTRIES, INC. (US) 1981-11-10 US disclosed
US-4229274-A PHOTOINITIATOR, PHOTOSENSITIZER, QUENCHER, AND COMPOUNDS CONTAINING ACRYLYLOXY GROUPS PPG INDUSTRIES, INC. (US) 1980-10-21 US disclosed