Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CFD | P00746 | 2/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3833716 | 0.82 | GAA (0.57) | POLBMEN1KMT2AKDM4EMAPT | |
| SCHEMBL502877 | 0.79 | AKR1B1 (0.58) | POLBMEN1KMT2AKDM4EMAPT | |
| SCHEMBL28603326 | 0.77 | HMGCR (0.61) | POLBMEN1KMT2AKDM4EMAPT | |
| Alcohol SCHEMBL22343921 | 0.75 | AKR1B1 (0.50) | POLBMEN1KMT2AKDM4EMAPT | |
| SCHEMBL15760015 | 0.75 | HSD17B10 (0.57) | POLBMEN1KMT2AKDM4EMAPT | |
| SCHEMBL24791740 | 0.75 | CYP4F2 (0.47) | POLBMEN1KMT2AKDM4EMAPT | |
| SCHEMBL30745363 | 0.75 | CYP4F2 (0.47) | POLBMEN1KMT2AKDM4EMAPT | |
| SCHEMBL11150608 | 0.74 | KDM4E (0.43) | POLBMEN1KMT2AKDM4EMAPT | |
| SCHEMBL28877435 | 0.74 | TOP1 (0.47) | POLBMEN1KMT2AKDM4EMAPT | |
| SCHEMBL2445135 | 0.73 | HSD17B10 (0.51) | KDM4EGAAALDH1A1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832654-B1 | Radiation protection agents suitable for use with radiopharmaceuticals comprising reducible active ingredients | NIHON MEDIPHYSICS CO LTD (JP) | 2003-01-15 | — | — | EP | disclosed |