Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.44 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.44 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.44 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28877452 | 0.83 | TOP1 (0.43) | TOP1KMT2AMEN1MAPTKDM4E | |
| SCHEMBL30032466 | 0.82 | NR1H4 (0.56) | GAANR1H4NPC1TP53LMNA | |
| SCHEMBL23796529 | 0.82 | NR1H4 (0.56) | GAANR1H4NPC1TP53LMNA | |
| SCHEMBL28877448 | 0.81 | MEN1 (0.56) | TOP1KMT2AMEN1KDM4EPOLB | |
| SCHEMBL11691503 | 0.80 | MEN1 (0.61) | TOP1KMT2AMEN1MAPTKDM4E | |
| SCHEMBL23796274 | 0.80 | KMT2A (0.51) | KMT2AMEN1MAPTKDM4EPOLB | |
| SCHEMBL28877417 | 0.80 | NR1H4 (0.49) | TOP1KMT2AMEN1MAPTKDM4E | |
| SCHEMBL28877413 | 0.78 | TOP1 (0.48) | TOP1KMT2AMEN1MAPTKDM4E | |
| SCHEMBL23796620 | 0.76 | NR1H4 (0.43) | GAANR1H4NPC1TP53LMNA | |
| SCHEMBL30032625 | 0.76 | NR1H4 (0.43) | GAANR1H4NPC1TP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115279730-A | 2, 5-or 2, 6-disubstituted hydroquinone derivatives having at least one carboxyl, sulfo or amido group useful as medicaments | OM药物公司 | 2022-11-01 | — | — | CN | claimed |