Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 10/20 | 0.33 |
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6219120 | 0.90 | CNR1 (0.37) | EPHX1EPHX2SCN5AMCHR1CNR1 | |
| SCHEMBL4840751 | 0.88 | CNR1 (0.47) | EPHX1EPHX2SCN5AMCHR1CNR1 | |
| SCHEMBL6218812 | 0.81 | ITGAL (0.36) | EPHX1EPHX2SCN5AMCHR1METAP2 | |
| SCHEMBL14254759 | 0.80 | ITGAL (0.36) | EPHX1EPHX2SCN5AMCHR1METAP2 | |
| SCHEMBL14254855 | 0.79 | ITGAL (0.46) | EPHX2CNR1METAP2 | |
| SCHEMBL6215949 | 0.78 | ITGAL (0.36) | EPHX1EPHX2SCN5AMCHR1 | |
| SCHEMBL4840734 | 0.78 | EPHX1 (0.36) | EPHX1EPHX2SCN5AMCHR1METAP2 | |
| SCHEMBL4847326 | 0.77 | ITGAL (0.39) | METAP2 | |
| SCHEMBL4847498 | 0.77 | ITGAL (0.39) | METAP2 | |
| SCHEMBL4848864 | 0.76 | LMNA (0.39) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307455-A2 | INHIBITORS OF ALPHA-L BETA-2 MEDIATED CELL ADHESION | TANABE SEIYAKU CO., LTD. (JP) | 2003-05-07 | — | — | EP | disclosed |
| WO-2001030781-A2 | INHIBITORS OF αLβ2 MEDIATED CELL ADHESION | TANABE SEIYAKU CO., LTD. (JP) | 2001-05-03 | — | — | WO | disclosed |