Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 5/20 | 0.75 |
| ▸ | CTSV | O60911 | 4/20 | 0.75 |
| ▸ | CTSL | P07711 | 3/20 | 0.75 |
| ▸ | CTSK | P43235 | 4/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ACE | P12821 | 7/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 5/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6808619 | 1.00 | CTSS (0.75) | CTSSCTSVCTSLCTSKKMT2A | |
| SCHEMBL4446626 | 1.00 | CTSS (0.75) | CTSSCTSVCTSLCTSKKMT2A | |
| SCHEMBL13677203 | 1.00 | CTSS (0.75) | CTSSCTSVCTSLCTSKKMT2A | |
| SCHEMBL4452619 | 0.94 | CTSS (0.70) | CTSSCTSVCTSLCTSKKMT2A | |
| SCHEMBL13677164 | 0.94 | CTSS (0.70) | CTSSCTSVCTSLCTSKKMT2A | |
| SCHEMBL7100155 | 0.94 | CTSS (0.70) | CTSSCTSVCTSLCTSKKMT2A | |
| SCHEMBL4454178 | 0.94 | CTSS (0.70) | CTSSCTSVCTSLCTSKKMT2A | |
| SCHEMBL6804296 | 0.94 | CTSS (0.70) | CTSSCTSVCTSLCTSKACE | |
| SCHEMBL6800638 | 0.93 | CTSS (0.69) | CTSSCTSVCTSLCTSKKMT2A | |
| SCHEMBL6804704 | 0.93 | CTSS (0.69) | CTSSCTSVCTSLCTSKKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362052-A1 | INHIBITORS OF CRUZIPAIN AND OTHER CYSTEINE PROTEASES | Amura Therapeutics Limited (GB) | 2003-11-19 | — | — | EP | disclosed |
| WO-2002057270-A1 | INHIBITORS OF CRUZIPAIN AND OTHER CYSTEINE PROTEASES | AMURA THERAPEUTICS LIMITED (GB) | 2002-07-25 | — | — | WO | disclosed |