Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL185067 | 0.90 | MEN1 (0.44) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL4596956 | 0.88 | MEN1 (0.65) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL4597235 | 0.88 | MEN1 (0.65) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL7207955 | 0.88 | MEN1 (0.65) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL4595342 | 0.88 | MEN1 (0.65) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL8596334 | 0.87 | TSHR (0.42) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL5940404 | 0.85 | MEN1 (0.61) | MEN1KMT2ATSHRMAPK1THRB | |
| Triethylene Glycol SCHEMBL8468778 | 0.85 | MEN1 (0.69) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL6800013 | 0.85 | TSHR (0.62) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL3909091 | 0.83 | MEN1 (0.58) | MEN1KMT2ATSHRMAPK1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200247927-A1 | CONTROL OF POLYMER NETWORK STRUCTURES VIA NANOGELS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2020-08-06 | — | — | US | claimed |
| US-20030065056-A1 | A five membered ring containing a ketone or thione group and having atleast 2 sulfur atom when its carbonate or one thio and one sulfur when its thione compound, and a compound having two or more acidic groups | KYOWA YUKA CO., LTD. (JP) | 2003-04-03 | — | — | US | disclosed |
| EP-1260555-A1 | Resin compositions | Kyowa Yuka Co., Ltd. (JP) | 2002-11-27 | — | — | EP | disclosed |