Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL185067 | 0.98 | MEN1 (0.44) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL7106366 | 0.87 | MEN1 (0.50) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL3841379 | 0.84 | TSHR (0.50) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL6800013 | 0.82 | TSHR (0.62) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL14198257 | 0.80 | MEN1 (0.58) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Triethylene Glycol SCHEMBL28925083 | 0.80 | MEN1 (0.58) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL25885638 | 0.79 | TSHR (0.50) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL15463146 | 0.79 | TSHR (0.50) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL4597235 | 0.79 | MEN1 (0.65) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL10506890 | 0.79 | TSHR (0.59) | TSHRMAPK1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0630927-B1 | Optical urethane resin | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-09-16 | — | — | EP | disclosed |
| US-5576412-A | POLYURETHANES FORMED BY REACTION OF ALCOHOL OR MERCAPTAN WITH ISO(THIO)CYANATE COMPOUND | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-11-19 | — | — | US | disclosed |
| EP-0630927-A2 | Optical urethane resin | Takeda Chemical Industries, Ltd. (JP) | 1994-12-28 | — | — | EP | disclosed |