Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 7/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.41 |
| ▸ | PSMB9 | P28065 | 4/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | PSMB10 | P40306 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7110084 | 0.81 | STS (0.53) | ALDH1A1POLBMMP1MMP2MMP3 | |
| SCHEMBL7107638 | 0.80 | MMP2 (0.40) | ACACBALDH1A1POLBMMP1MMP2 | |
| SCHEMBL7109650 | 0.76 | MEN1 (0.41) | ALDH1A1POLBPSMB8PSMB5KMT2A | |
| SCHEMBL7109849 | 0.75 | MEN1 (0.41) | ALDH1A1POLBMMP1MMP2MMP3 | |
| SCHEMBL7109620 | 0.75 | MEN1 (0.41) | ALDH1A1POLBMMP1MMP2MMP3 | |
| SCHEMBL20821123 | 0.73 | PSMB8 (0.60) | ACACBITGB1ITGA4PSMB8PSMB5 | |
| SCHEMBL20821120 | 0.73 | PSMB8 (0.54) | ACACBITGB1ITGA4PSMB8PSMB5 | |
| SCHEMBL16118918 | 0.72 | PSMB8 (0.78) | PSMB8PSMB5PSMB9PSMB10PSMB2 | |
| SCHEMBL16119358 | 0.72 | PSMB8 (0.78) | PSMB8PSMB5PSMB9PSMB10PSMB2 | |
| SCHEMBL16118930 | 0.72 | PSMB8 (0.78) | PSMB8PSMB5PSMB9PSMB10PSMB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030013725-A1 | Amino acid derivatives | ONO PHARMACEUTICAL CO., LTD. | 2003-01-16 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030013725-A1 | Amino acid derivatives | CACNA1B, SCN1A, SCN2A | ACACB 1823/4885ITGB1 2162/4885ITGA4 4190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.