SCHEMBL7106624

SCHEMBL7106624

CCC(C)OC(=O)C(C)(Cl)Cl

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MMP8 P22894 1/20 0.34
MAPT P10636 2/20 0.33
TP53 P04637 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11345569 0.84 MAPT (0.33) MAPTTP53LMNA
SCHEMBL28568057 0.83 MAPT (0.31) MAPT
SCHEMBL2479166 0.82 PRKCA (0.44) MMP8MAPTTP53LMNA
SCHEMBL2976274 0.82 PRKCA (0.44) MMP8MAPTTP53LMNA
SCHEMBL2980891 0.82 PRKCA (0.44) MMP8MAPTTP53LMNA
SCHEMBL23292892 0.80 PRKCA (0.34) MMP8MAPT
SCHEMBL4678127 0.80 MAPT (0.33) MMP8MAPT
SCHEMBL28727629 0.80 MAPT (0.33) MMP8MAPT
SCHEMBL20747614 0.78 CA12 (0.33) MMP8MAPTLMNA
SCHEMBL20747710 0.78 CA12 (0.33) MMP8MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0967230-B1 Catalyst system for the preparation of olefin (co)polymers BAYER AG (DE) 2003-01-02 EP disclosed
US-6180554-B1 ORGANOALUMINUM COMPOUND, GROUP IV-VI METAL COMPOUND, AND MONO-OR DIHALOCARBOXYLIC ACID ALKYL ESTER REACTIVATOR BAYER AKTIENGESELLSCHAFT (DE) 2001-01-30 US disclosed
EP-0967230-A1 Catalyst system for the preparation of olefin (co)polymers Bayer Aktiengesellschaft (DE) 1999-12-29 EP disclosed