Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.39 |
| ▸ | HRH1 | P35367 | 3/20 | 0.39 |
| ▸ | DRD3 | P35462 | 3/20 | 0.39 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | EBP | Q15125 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 4/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD1 | P21728 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | DRD5 | P21918 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7106664 | 0.92 | LTA4H (0.41) | LTA4HHRH3HRH1DRD3PSMB1 | |
| SCHEMBL7113234 | 0.84 | EBP (0.45) | LTA4HHRH3EBPSIGMAR1ALDH1A1 | |
| SCHEMBL7106662 | 0.82 | ESR1 (0.44) | LTA4HHRH3HRH1DRD3PSMB1 | |
| SCHEMBL7110645 | 0.79 | EBP (0.48) | LTA4HHRH3PSMB1PSMB5EBP | |
| SCHEMBL7110262 | 0.78 | LTA4H (0.57) | LTA4HHRH3PSMB1PSMB5EBP | |
| SCHEMBL7113233 | 0.77 | EBP (0.46) | LTA4HHRH3EBPSIGMAR1ESR1 | |
| SCHEMBL7110148 | 0.76 | EBP (0.53) | LTA4HHRH3EBPSIGMAR1MCHR1 | |
| SCHEMBL7113006 | 0.76 | ESR1 (0.49) | EBPSIGMAR1MCHR1ESR1ESR2 | |
| SCHEMBL7111179 | 0.76 | EBP (0.46) | LTA4HHRH3EBPSIGMAR1ESR1 | |
| SCHEMBL7106078 | 0.73 | EBP (0.49) | LTA4HHRH3EBPSIGMAR1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030100754-A1 | NAPHTHALENE COMPOUNDS, INTERMEDIATES, FORMULATIONS, AND METHODS | ELI LILLY AND COMPANY | 2003-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030100754-A1 | NAPHTHALENE COMPOUNDS, INTERMEDIATES, FORMULATIONS, AND METHODS | NDC1, SQLE, NQO1 | LTA4H 418/4885HRH3 1647/4885HRH1 402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.