Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 15/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 3/20 | 0.51 |
| ▸ | F9 | P00740 | 1/20 | 0.49 |
| ▸ | F10 | P00742 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25437283 | 0.87 | STING1 (0.54) | STING1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9204578 | 0.84 | STING1 (0.63) | STING1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL1589579 | 0.84 | STING1 (0.68) | STING1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL10401001 | 0.83 | F9 (0.68) | STING1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL1590372 | 0.83 | STING1 (0.61) | STING1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL1590345 | 0.83 | STING1 (0.61) | STING1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL10692662 | 0.82 | STING1 (0.50) | STING1HDAC3HDAC4HDAC1HDAC7 | |
| Hydrochloric Acid SCHEMBL7276075 | 0.81 | F9 (0.67) | STING1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL10400717 | 0.81 | HDAC1 (0.80) | STING1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL20049489 | 0.80 | HDAC3 (0.64) | STING1HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0158380-B1 | BENZOTHIAZOLE AND BENZOTHIOPHENE DERIVATIVES | AKZO N.V. (NL) | 1989-01-11 | — | — | EP | claimed |
| EP-0158380-A1 | Benzothiazole and benzothiophene derivatives | AKZO N.V. (NL) | 1985-10-16 | — | — | EP | claimed |
| US-20030109570-A1 | Activate a peroxisome proliferator-activated receptor (PPAR) alpha or gamma which is an intranuclear transcription factor. The compound may be used as an active ingredient to give a drug for preventing or treating a variety of diseases | MITSUI CHEMICALS, INC. (JP) | 2003-06-12 | — | — | US | disclosed |
| EP-1284265-A1 | BENZOTHIOPHENE DERIVATIVES AND MEDICINAL USE THEREOF | Mitsui Chemicals, Inc. (JP) | 2003-02-19 | — | — | EP | disclosed |
| US-4929636-A | Positive inotrophic benzothiazole and benzothiophene compositions and method of use therefor | AKZO N.V. (NL) | 1990-05-29 | — | — | US | disclosed |
| EP-0158380-B1 | BENZOTHIAZOLE AND BENZOTHIOPHENE DERIVATIVES | AKZO N.V. (NL) | 1989-01-11 | — | — | EP | disclosed |
| US-4665206-A | Benzothiophene derivatives | AKZO N.V. (NL) | 1987-05-12 | — | — | US | disclosed |
| EP-0158380-A1 | Benzothiazole and benzothiophene derivatives | AKZO N.V. (NL) | 1985-10-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030109570-A1 | Activate a peroxisome proliferator-activated receptor (PPAR) alpha or gamma which is an intranuclear transcription factor. The compound may be used as an active ingredient to give a drug for preventing or treating a variety of diseases | PPARG, PPARA, PPARD | STING1 878/4885HDAC3 160/4885HDAC4 248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.