Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 8/20 | 0.39 |
| ▸ | CTSK | P43235 | 6/20 | 0.39 |
| ▸ | CTSL | P07711 | 6/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 7/20 | 0.39 |
| ▸ | CTSG | P08311 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7106872 | 1.00 | PTPN1 (0.42) | PTPN1GAARAB9ACTSSCTSK | |
| Trifluoroacetic Acid SCHEMBL6166382 | 0.94 | PTPN1 (0.42) | PTPN1GAARAB9ACTSSCTSK | |
| Trifluoroacetic Acid SCHEMBL6166385 | 0.94 | PTPN1 (0.42) | PTPN1GAARAB9ACTSSCTSK | |
| Trifluoroacetic Acid SCHEMBL6164344 | 0.87 | CTSB (0.43) | PTPN1GAARAB9ACTSSCTSK | |
| Trifluoroacetic Acid SCHEMBL6164351 | 0.87 | CTSB (0.43) | PTPN1GAARAB9ACTSSCTSK | |
| Trifluoroacetic Acid SCHEMBL7106869 | 0.85 | F10 (0.44) | PTPN1GAARAB9ACTSSCTSK | |
| Trifluoroacetic Acid SCHEMBL6164347 | 0.80 | F10 (0.58) | F10 | |
| Trifluoroacetic Acid SCHEMBL6166758 | 0.80 | CTSB (0.41) | GAARAB9ACTSSCTSKCTSL | |
| Trifluoroacetic Acid SCHEMBL6166384 | 0.80 | PTPN1 (0.42) | PTPN1GAARAB9ACTSSCTSK | |
| Trifluoroacetic Acid SCHEMBL6166754 | 0.80 | CTSB (0.41) | GAARAB9ACTSSCTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030065176-A1 | Factor xa inhibitors with aryl-amidines and derivatives, and prodrugs thereof | LG CHEM INVESTMENT LTD. (KR) | 2003-04-03 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065176-A1 | Factor xa inhibitors with aryl-amidines and derivatives, and prodrugs thereof | F2, F12, TFPI | PTPN1 1142/4885GAA 815/4885RAB9A 2909/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.