Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 9/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 9/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 8/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.43 |
| ▸ | NT5E | P21589 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7106895 | 1.00 | ADORA3 (0.48) | ADORA3ADORA2AADORA1ADORA2BNT5E | |
| SCHEMBL7103592 | 0.92 | ADORA3 (0.48) | ADORA3ADORA2AADORA1ADORA2BNT5E | |
| SCHEMBL7103589 | 0.92 | ADORA3 (0.48) | ADORA3ADORA2AADORA1ADORA2BNT5E | |
| SCHEMBL7103782 | 0.90 | ADORA3 (0.47) | ADORA3ADORA2AADORA1ADORA2BNT5E | |
| SCHEMBL7103784 | 0.90 | ADORA3 (0.47) | ADORA3ADORA2AADORA1ADORA2BNT5E | |
| SCHEMBL7104759 | 0.86 | ADORA3 (0.48) | ADORA3ADORA2AADORA1ADORA2BNT5E | |
| SCHEMBL7762177 | 0.86 | ADORA3 (0.49) | ADORA3ADORA2AADORA1ADORA2BNT5E | |
| SCHEMBL7762181 | 0.86 | ADORA3 (0.49) | ADORA3ADORA2AADORA1ADORA2BNT5E | |
| SCHEMBL7202879 | 0.85 | ADORA2A (0.48) | ADORA3ADORA2AADORA1ADORA2BNT5E | |
| SCHEMBL7104888 | 0.83 | ADORA2A (0.48) | ADORA3ADORA2AADORA1ADORA2BNT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1090023-B1 | 2-(PURIN-9-YL)-TETRAHYDROFURAN-3,4-DIOL DERIVATIVES | GLAXO GROUP LTD (GB) | 2003-09-10 | — | — | EP | disclosed |