Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 2/20 | 0.42 |
| ▸ | RARG | P13631 | 2/20 | 0.42 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 4/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.39 |
| ▸ | ENTPD5 | O75356 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7106142 | 0.98 | RARB (0.40) | RARBRARGRARAOPRM1GLA | |
| SCHEMBL10899122 | 0.86 | RARB (0.50) | RARBRARGRARAOPRM1GLA | |
| SCHEMBL12733160 | 0.81 | RARB (0.47) | RARBRARGRARAOPRM1GLA | |
| SCHEMBL17877422 | 0.80 | ESR1 (0.42) | OPRM1ESR1ESR2ALDH1A1MAPT | |
| SCHEMBL6492178 | 0.79 | ENTPD5 (0.40) | OPRM1ESR1ESR2ENTPD5OPRD1 | |
| SCHEMBL2213384 | 0.78 | RARB (0.42) | RARBRARGRARAOPRM1GLA | |
| SCHEMBL24666355 | 0.76 | ESR1 (0.38) | OPRM1ESR1ESR2ENTPD5ALDH1A1 | |
| SCHEMBL29820150 | 0.76 | ESR1 (0.38) | OPRM1ESR1ESR2ENTPD5ALDH1A1 | |
| SCHEMBL7211111 | 0.75 | CYP3A4 (0.44) | OPRM1ESR1ESR2ALDH1A1MAPT | |
| SCHEMBL29911088 | 0.75 | CYP3A4 (0.44) | OPRM1ESR1ESR2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0904774-B1 | Resorcinol derivatives | PFIZER PROD INC (US) | 2003-03-26 | — | — | EP | disclosed |
| US-6132740-A | SKIN LIGHTENING AGENTS; TYROSINASE INHIBITORS; ANTIINFLAMMATORY AGENTS; 4-CYCLOPENTYL- OR CYCLOPENTENYLRESORCINOLS | PFIZER INC. (US) | 2000-10-17 | — | — | US | disclosed |
| WO-1999015148-A1 | RESORCINOL DERIVATIVES | PFIZER PRODUCTS INC. (US) | 1999-04-01 | — | — | WO | disclosed |
| EP-0904774-A1 | Resorcinol derivatives | Pfizer Products Inc. (US) | 1999-03-31 | — | — | EP | disclosed |