Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENTPD5 | O75356 | 2/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
| ▸ | POLA1 | P09884 | 2/20 | 0.34 |
| ▸ | SHBG | P04278 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | SOD1 | P00441 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7106142 | 0.80 | RARB (0.40) | ENTPD5OPRM1OPRK1OPRD1ESR1 | |
| SCHEMBL7106913 | 0.79 | RARB (0.42) | ENTPD5OPRM1OPRK1OPRD1ESR1 | |
| SCHEMBL10725944 | 0.67 | SOD1 (0.41) | HSD11B1OPRK1OPRD1SOD1 | |
| SCHEMBL10725940 | 0.67 | SOD1 (0.41) | HSD11B1OPRK1OPRD1SOD1 | |
| SCHEMBL10749068 | 0.67 | SOD1 (0.41) | HSD11B1OPRK1OPRD1SOD1 | |
| SCHEMBL10899122 | 0.66 | RARB (0.50) | ENTPD5OPRM1OPRK1OPRD1ESR1 | |
| SCHEMBL24170557 | 0.65 | OPRM1 (0.53) | HSD11B1OPRM1OPRK1OPRD1 | |
| SCHEMBL8620209 | 0.65 | OPRM1 (0.53) | HSD11B1OPRM1OPRK1OPRD1 | |
| SCHEMBL17877422 | 0.64 | ESR1 (0.42) | OPRM1ESR1ESR2 | |
| SCHEMBL10529159 | 0.64 | ESR2 (0.59) | HSD11B1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050143594-A1 | Process for preparing resorcinol derivatives | BRADLEY STUART E (GB) | 2005-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143594-A1 | Process for preparing resorcinol derivatives | CYP4B1, CYP4A11, POR | ENTPD5 1349/4885HSD11B1 117/4885OPRM1 2628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.