SCHEMBL7106925

SCHEMBL7106925

CC(C)=C[C@@H]1[C@@H](C(=O)Cl)C1(C)C

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.55
ALOX15 P16050 1/20 0.42
TSHR P16473 5/20 0.41
CYP1A2 P05177 4/20 0.41
CYP2C19 P33261 4/20 0.41
NPSR1 Q6W5P4 2/20 0.41
CYP3A4 P08684 2/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
HPGD P15428 1/20 0.38
TDP1 Q9NUW8 3/20 0.36
TRPV1 Q8NER1 1/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
MAPT P10636 2/20 0.36
HTT P42858 2/20 0.36
ALDH1A1 P00352 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
POLB P06746 1/20 0.35
RAB9A P51151 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7106923 1.00 LMNA (0.55) LMNAALOX15TSHRCYP1A2CYP2C19
SCHEMBL554915 1.00 LMNA (0.55) LMNAALOX15TSHRCYP1A2CYP2C19
SCHEMBL11502263 1.00 LMNA (0.55) LMNAALOX15TSHRCYP1A2CYP2C19
SCHEMBL8409028 1.00 LMNA (0.55) LMNAALOX15TSHRCYP1A2CYP2C19
SCHEMBL16606352 0.87 LMNA (0.42) LMNATSHRCYP1A2CYP2C19NPSR1
SCHEMBL3885618 0.87 LMNA (0.42) LMNATSHRCYP1A2CYP2C19NPSR1
SCHEMBL3885619 0.87 LMNA (0.42) LMNATSHRCYP1A2CYP2C19NPSR1
SCHEMBL3885617 0.87 LMNA (0.42) LMNATSHRCYP1A2CYP2C19NPSR1
SCHEMBL9021196 0.86 HPGD (0.47) LMNATSHRCYP1A2CYP2C19NPSR1
SCHEMBL7102385 0.86 HPGD (0.47) LMNATSHRCYP1A2CYP2C19NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018050213-A1 IMPROVED PROCESS FOR THE PREPARATION OF PYRETHROIDS ENDURA S.P.A. (IT) 2018-03-22 WO disclosed
US-9487471-B1 Synthesis of pyrethroids and pyrethroid-containing compositions PROVIVI, INC. (US) 2016-11-08 US disclosed
US-9487471-B1 Synthesis of pyrethroids and pyrethroid-containing compositions PROVIVI, INC. (US) 2016-11-08 US disclosed
EP-0963976-B1 Oxyimino-substituted cyclopropanecarboxylate pesticides SUMITOMO CHEMICAL CO (JP) 2003-02-19 EP disclosed
EP-0939073-B1 Ester of 2,2-dimethyl-cyclopropanecarboxylic acid and their use as pesticides SUMITOMO CHEMICAL CO (JP) 2002-12-04 EP disclosed
EP-0926129-B1 Ester compound and pesticide containing it SUMITOMO CHEMICAL CO (JP) 2002-03-20 EP disclosed
US-6225495-B1 PESTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-05-01 US disclosed
US-6034128-A PESTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-03-07 US disclosed
EP-0963976-A1 Oxyimino-substituted cyclopropanecarboxylate pesticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-12-15 EP disclosed
EP-0939073-A1 Ester of 2,2-dimethyl-cyclopropanecarboxylic acid and their use as pesticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-09-01 EP disclosed
US-4774369-A ALCOHOLS AS INTERMEDIATES FOR INSECTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-09-27 US disclosed
US-4714712-A Carboxylic acid esters and insecticides containing them as the active ingredient SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-12-22 US disclosed
EP-0061880-B1 PROCESS FOR PREPARING RACEMIZED CYCLOPROPANECARBOXYLIC ACIDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-06-19 EP disclosed
US-4485257-A TREATMENT WITH A LEWIS ACID; INSESTICIDAL USE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-11-27 US disclosed
US-4450169-A PESTICIDES; NEMATOCIDES; FUNGICIDES; MITICIDES; REPELLANTS ROUSSEL UCLAF (FR) 1984-05-22 US disclosed
EP-0061880-A1 Process for preparing racemized cyclopropanecarboxylic acids SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-10-06 EP disclosed
US-4315868-A Process for the preparation of α-cyanobenzyl esters ROUSSEL UCLAF (FR) 1982-02-16 US disclosed
US-4277617-A Process for the preparation of esters ROUSSEL UCLAF (FR) 1981-07-07 US disclosed
US-4182906-A BORON HALIDE CATALYST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1980-01-08 US disclosed
US-3989750-A LEWIS ACID SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-11-02 US disclosed