Oleanolic_Acid

Oleanolic_Acid

SCHEMBL71070

CC1(C)CC[C@]2(C(=O)O)CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]2C1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 12/20 1.00
PTPN2 P17706 4/20 1.00
F3 P13726 4/20 1.00
POLB P06746 3/20 1.00
USP7 Q93009 3/20 1.00
AKR1B10 O60218 3/20 1.00
GPBAR1 Q8TDU6 3/20 1.00
PSMB11 A5LHX3 2/20 1.00
PSMA7 O14818 2/20 1.00
PLA2G1B P04054 2/20 1.00
PTPRC P08575 2/20 1.00
PTPRF P10586 2/20 1.00
PSMB1 P20618 2/20 1.00
CES1 P23141 2/20 1.00
ACP1 P24666 2/20 1.00
PSMA1 P25786 2/20 1.00
PSMA2 P25787 2/20 1.00
PSMA3 P25788 2/20 1.00
PSMA4 P25789 2/20 1.00
PSMB8 P28062 2/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oleanolic_Acid SCHEMBL15714063 1.00 PTPN1 (1.00) PTPN1PTPN2F3POLBUSP7
Oleanolic_Acid SCHEMBL12337275 1.00 PTPN1 (1.00) PTPN1PTPN2F3POLBUSP7
Oleanolic_Acid SCHEMBL18420569 1.00 PTPN1 (1.00) PTPN1PTPN2F3POLBUSP7
Oleanolic_Acid SCHEMBL13425080 1.00 PTPN1 (1.00) PTPN1PTPN2F3POLBUSP7
Oleanolic_Acid SCHEMBL13395360 1.00 PTPN1 (1.00) PTPN1PTPN2F3POLBUSP7
Oleanolic_Acid SCHEMBL16153016 1.00 PTPN1 (1.00) PTPN1PTPN2F3POLBUSP7
Oleanolic_Acid SCHEMBL24916648 1.00 PTPN1 (1.00) PTPN1PTPN2F3POLBUSP7
Oleanolic_Acid SCHEMBL21892159 1.00 PTPN1 (1.00) PTPN1PTPN2F3POLBUSP7
Oleanolic_Acid SCHEMBL22009261 1.00 PTPN1 (1.00) PTPN1PTPN2F3POLBUSP7
Oleanolic_Acid SCHEMBL20904290 1.00 PTPN1 (1.00) PTPN1PTPN2F3POLBUSP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 27432 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144740-A1 COSMETIC ACTIVE INGREDIENT DERIVED FROM A NON-VOLATILE FRACTION OF CANARIUM EXUDATE AND USES THEREOF FLORE SCOLA (FR) 2026-05-28 US claimed
EP-4748438-A2 ENTERICALLY DELIVERED BITTER OLIGOPEPTIDES FOR THE TREATMENT FOR TYPE 2 DIABETES Cedars-Sinai Medical Center (US) 2026-05-27 EP claimed
CN-121914965-B Serum-free culture medium for proliferation of bovine muscle stem cells and application thereof NANJING AGRICULTURAL UNIVERSITY (CN) 2026-05-26 CN claimed
CN-119424331-B Oleanolic acid modified HG type pectin nano micelle and preparation method and application thereof Hunan academy of agricultural sciences (CN) 2026-05-26 CN claimed
CN-122074632-A Spice extracting solution for brewing cooking wine and preparation method thereof 2026-05-26 CN claimed
CN-122080106-A Oleanolic acid acylhydrazone derivative and preparation method and application thereof 2026-05-26 CN claimed
CN-122074602-A High-protein biological fermentation type aquatic feed and preparation method thereof 2026-05-26 CN claimed
CN-122075613-A Traditional Chinese medicine composition for treating cancer pain and numbness and preparation and application thereof 2026-05-26 CN claimed
CN-122081024-A Preparation method of traditional Chinese medicine fermented wine 2026-05-26 CN claimed
US-20260137751-A1 ENTERICALLY DELIVERED BITTER OLIGOPEPTIDES FOR THE TREATMENT FOR TYPE 2 DIABETES CEDARS-SINAI MEDICAL CENTER (US) 2026-05-21 US claimed
US-4808629-A Safe antileukemia drug, SAL LIU YAGUANG (US) 1989-02-28 US claimed
US-4789752-A REACTING HALIDES WITH ALCOHOLS IN SOLVENT, ADDING ACID ACCEPTORS HUELS TROISDORF AKTIENGESELLSCHAFT (DE) 1988-12-06 US claimed
US-4752606-A OLEANOLIC ACID-ANTIULCER AGENT 501 Noristan Limited (ZA) 1988-06-21 US claimed
US-4675318-A Safe antileukemia drug, SAL LIU YAGUANG (US) 1987-06-23 US claimed
EP-0213809-A2 Extract of swertia japonica makino and method of obtaining the same Kabushiki Kaisha Vitamin Kenkyusyo (JP) 1987-03-11 EP claimed
EP-0203386-A2 Pharmaceutical composition for treating nonlymphatic leukemia and method of producing the same and its components Liu, Yaguang (US) 1986-12-03 EP claimed
EP-0093520-B1 PHARMACEUTICAL COMPOSITIONS AND PREPARATION THEREOF NORISTAN LIMITED (ZA) 1986-10-15 EP claimed
US-4606911-A PENTACYCLIC ACID TRITERPENES ROHTO PHARMACEUTICAL CO. LTD. (JP) 1986-08-19 US claimed
EP-0093520-A1 Pharmaceutical compositions and preparation thereof NORISTAN LIMITED (ZA) 1983-11-09 EP claimed
EP-0012225-B1 ALDEHYDES, THEIR PREPARATION AND THEIR USE AS PERFUMES Henkel Kommanditgesellschaft auf Aktien (DE) 1982-07-28 EP claimed