Oleanolic_Acid

Oleanolic_Acid

SCHEMBL13455967

CC1(C)CC[C@]2(C(=O)O)CCC3(C)C(=CCC4[C@@]5(C)CCC(O)C(C)(C)C5CC[C@]43C)[C@@H]2C1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PTPN1 P18031 12/20 1.00
▸ PTPN2 P17706 4/20 1.00
▸ F3 P13726 4/20 1.00
▸ POLB P06746 3/20 1.00
▸ USP7 Q93009 3/20 1.00
▸ AKR1B10 O60218 3/20 1.00
▸ GPBAR1 Q8TDU6 3/20 1.00
▸ PSMB11 A5LHX3 2/20 1.00
▸ PSMA7 O14818 2/20 1.00
▸ PLA2G1B P04054 2/20 1.00
▸ PTPRC P08575 2/20 1.00
▸ PTPRF P10586 2/20 1.00
▸ PSMB1 P20618 2/20 1.00
▸ CES1 P23141 2/20 1.00
▸ ACP1 P24666 2/20 1.00
▸ PSMA1 P25786 2/20 1.00
▸ PSMA2 P25787 2/20 1.00
▸ PSMA3 P25788 2/20 1.00
▸ PSMA4 P25789 2/20 1.00
▸ PSMB8 P28062 2/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oleanolic_Acid SCHEMBL71070 1.00 PTPN1 (1.00) PTPN1PTPN2F3POLBUSP7
Oleanolic_Acid SCHEMBL15382987 1.00 PTPN1 (1.00) PTPN1PTPN2F3POLBUSP7
Oleanolic_Acid SCHEMBL16126185 1.00 PTPN1 (1.00) PTPN1PTPN2F3POLBUSP7
Oleanolic_Acid SCHEMBL12313106 1.00 PTPN1 (1.00) PTPN1PTPN2F3POLBUSP7
Oleanolic_Acid SCHEMBL18688362 1.00 PTPN1 (1.00) PTPN1PTPN2F3POLBUSP7
Oleanolic_Acid SCHEMBL24916648 1.00 PTPN1 (1.00) PTPN1PTPN2F3POLBUSP7
Oleanolic_Acid SCHEMBL21892159 1.00 PTPN1 (1.00) PTPN1PTPN2F3POLBUSP7
Oleanolic_Acid SCHEMBL22009261 1.00 PTPN1 (1.00) PTPN1PTPN2F3POLBUSP7
Oleanolic_Acid SCHEMBL20904290 1.00 PTPN1 (1.00) PTPN1PTPN2F3POLBUSP7
Oleanolic_Acid SCHEMBL16999276 1.00 PTPN1 (1.00) PTPN1PTPN2F3POLBUSP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100055163-A1 FORMULATION OF NATURAL TRITERPENES AND BIOPHENOLS OBTAINED FROM THE GENUS OLEA IN LIPOSOMES UNIVERSIDAD DE GRANADA (ES) 2010-03-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100055163-A1 FORMULATION OF NATURAL TRITERPENES AND BIOPHENOLS OBTAINED FROM THE GENUS OLEA IN LIPOSOMES LIPA, MGLL, LSS PTPN1 3281/4885PTPN2 2807/4885F3 1223/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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