Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 9/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7106164 | 0.89 | L3MBTL1 (0.41) | PTGIREPHX1HTTLMNAKMT2A | |
| SCHEMBL7107093 | 0.89 | PTGIR (0.48) | PTGIREPHX1HTTNOTUMSGMS2 | |
| SCHEMBL7654170 | 0.84 | PTGIR (0.52) | PTGIREPHX1NOTUMSGMS2 | |
| SCHEMBL7106168 | 0.76 | ATM (0.41) | PTGIREPHX1TDP1CHRM4CHRM3 | |
| SCHEMBL4186177 | 0.76 | EPHX1 (0.60) | EPHX1NOTUMKCNA5 | |
| SCHEMBL7110718 | 0.74 | CHRM4 (0.40) | PTGIRHTTLMNAKMT2ATDP1 | |
| SCHEMBL17092997 | 0.74 | ATM (0.53) | PTGIRHTTKMT2ATDP1ALDH1A1 | |
| SCHEMBL7105745 | 0.74 | L3MBTL1 (0.41) | PTGIRHTTKMT2ATDP1ALDH1A1 | |
| SCHEMBL7104989 | 0.74 | ATM (0.41) | PTGIRHTTKMT2ATDP1ALDH1A1 | |
| SCHEMBL7104164 | 0.73 | CHRM4 (0.39) | PTGIRLMNATDP1CHRM4CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1013639-B1 | Aryl carboxylic acid and tetrazole derivatives comprising a carbamoyloxy unit | HOFFMANN LA ROCHE (CH) | 2003-10-01 | — | — | EP | disclosed |
| EP-1013639-A1 | Aryl carboxylic acid and tetrazole derivatives comprising a carbamoyloxy unit | F. HOFFMANN-LA ROCHE AG (CH) | 2000-06-28 | — | — | EP | disclosed |