Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.36 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL198133 | 0.76 | HCAR2 (0.45) | HCAR2TAAR1LMNAKDM4EALDH1A1 | |
| SCHEMBL5892165 | 0.76 | CA1 (0.44) | HCAR2CA1CA2CA9CA12 | |
| SCHEMBL6272307 | 0.74 | HCAR2 (0.46) | HCAR2TAAR1LMNAKDM4EKMT2A | |
| Ammonia Solution, Strong SCHEMBL27871924 | 0.74 | HCAR2 (0.44) | HCAR2TAAR1LMNAKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL28273439 | 0.74 | ALDH1A1 (0.44) | HCAR2TAAR1LMNAKDM4EALDH1A1 | |
| Phosphine SCHEMBL20897413 | 0.74 | CYP2D6 (0.46) | HCAR2TAAR1LMNAKDM4EALDH1A1 | |
| SCHEMBL1792962 | 0.73 | PTGES2 (0.44) | CA1CA2CA9CA12CA7 | |
| SCHEMBL18028786 | 0.73 | PTGES2 (0.44) | CA1CA2CA9CA12CA7 | |
| SCHEMBL18028833 | 0.73 | PTGES2 (0.44) | CA1CA2CA9CA12CA7 | |
| SCHEMBL28040936 | 0.72 | CA1 (0.48) | CA1CA2CA9CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345591-A1 | PHARMACEUTICAL AEROSOL FORMULATION | AstraZeneca AB (SE) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002049616-A1 | PHARMACEUTICAL AEROSOL FORMULATION | ASTRAZENECA AB (SE) | 2002-06-27 | — | — | WO | disclosed |