Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | AVPR2 | P30518 | 6/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | AVPR1A | P37288 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7109575 | 0.85 | AVPR2 (0.51) | PDE4APDE4BPDE4CPDE4DAVPR2 | |
| SCHEMBL7115671 | 0.85 | AVPR2 (0.48) | PDE4APDE4BPDE4CPDE4DAVPR2 | |
| SCHEMBL5836585 | 0.83 | AVPR2 (0.48) | PDE4APDE4BPDE4CPDE4DAVPR2 | |
| SCHEMBL5785308 | 0.82 | AVPR2 (0.47) | PDE4APDE4BPDE4CPDE4DAVPR2 | |
| SCHEMBL7114677 | 0.81 | AVPR2 (0.49) | PDE4APDE4BPDE4CPDE4DAVPR2 | |
| SCHEMBL5835280 | 0.81 | AVPR2 (0.46) | PDE4APDE4BPDE4CPDE4DAVPR2 | |
| SCHEMBL7108357 | 0.80 | AVPR1A (0.52) | AVPR2AVPR1A | |
| SCHEMBL5782635 | 0.80 | PDE4A (0.45) | PDE4APDE4BPDE4CPDE4DAVPR2 | |
| SCHEMBL5787160 | 0.80 | AVPR2 (0.47) | PDE4APDE4BPDE4CPDE4DAVPR2 | |
| SCHEMBL5784354 | 0.80 | PDE4A (0.43) | PDE4APDE4BPDE4CPDE4DAVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030008863-A1 | Novel tricyclic diazepines tocolytic oxytocin receptor antagonists | WYETH | 2003-01-09 | — | — | US | claimed |
| US-20030008863-A1 | Novel tricyclic diazepines tocolytic oxytocin receptor antagonists | WYETH | 2003-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030008863-A1 | Novel tricyclic diazepines tocolytic oxytocin receptor antagonists | OXTR, OPRL1, HCRTR2 | PDE4A 2872/4885PDE4B 3655/4885PDE4C 3678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.