Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7943328 | 0.88 | MAPT (0.30) | — | |
| Hydrochloric Acid SCHEMBL454411 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL450411 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL451037 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL450582 | 0.79 | NPSR1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL7103369 | 0.78 | MAPT (0.31) | — | |
| Hydrochloric Acid SCHEMBL455913 | 0.77 | NPC1 (0.35) | — | |
| Hydrochloric Acid SCHEMBL450475 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL455537 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL450280 | 0.77 | NPC1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786466-B1 | Olefin polymerisation process which comprises a transition metal catalyst. | TOSOH CORP (JP) | 2003-04-16 | — | — | EP | disclosed |
| US-6316558-B1 | POLYMERIZING OLEFIN USING CATALYST COMPRISING TRANSITION METAL COMPOUND, COMPOUND CAPABLE OF A REACTING WITH TRANSITION METAL COMPOUND TO FORM A CATIONIC TRANSITION METAL COMPOUND, ORGANOMETALLIC TO FORM POLYOLEFIN | TOSOH CORPORATION (JP) | 2001-11-13 | — | — | US | disclosed |
| EP-0786466-A1 | Transition metal compound, olefin polymerization catalyst comprising the compound, and process for production of olefin polymer | Tosoh Corporation (JP) | 1997-07-30 | — | — | EP | disclosed |