Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PTGIR | P43119 | 6/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 5/20 | 0.39 |
| ▸ | CYBB | P04839 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7110721 | 0.88 | ATM (0.40) | ATMTDP1L3MBTL1PTGIRPTGDR | |
| SCHEMBL7107853 | 0.86 | ATM (0.41) | ATMTDP1L3MBTL1PTGIRPTGDR | |
| SCHEMBL7110593 | 0.85 | ATM (0.38) | ATMTDP1L3MBTL1PTGIRPTGDR | |
| SCHEMBL17092997 | 0.82 | ATM (0.53) | ATMTDP1L3MBTL1PTGIRPTGDR | |
| SCHEMBL7106168 | 0.82 | ATM (0.41) | ATMTDP1L3MBTL1PTGIRPTGDR | |
| SCHEMBL7104991 | 0.82 | ATM (0.41) | ATMTDP1L3MBTL1PTGIRPTGDR | |
| SCHEMBL7105749 | 0.82 | ATM (0.41) | ATMTDP1L3MBTL1PTGIRPTGDR | |
| SCHEMBL7653485 | 0.81 | PTGIR (0.48) | TDP1L3MBTL1PTGIRPTGDRPTGER4 | |
| SCHEMBL7104169 | 0.78 | ATM (0.39) | ATMTDP1L3MBTL1PTGIRPTGDR | |
| SCHEMBL27484026 | 0.78 | KMT2A (0.45) | ATMTDP1L3MBTL1AKR1B1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1013639-B1 | Aryl carboxylic acid and tetrazole derivatives comprising a carbamoyloxy unit | HOFFMANN LA ROCHE (CH) | 2003-10-01 | — | — | EP | disclosed |
| EP-1013639-A1 | Aryl carboxylic acid and tetrazole derivatives comprising a carbamoyloxy unit | F. HOFFMANN-LA ROCHE AG (CH) | 2000-06-28 | — | — | EP | disclosed |