Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | BID | P55957 | 3/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.37 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.37 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.37 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.37 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.37 |
| ▸ | PTGIR | P43119 | 1/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.36 |
| ▸ | IAPP | P10997 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7110721 | 0.90 | ATM (0.40) | ATMTDP1L3MBTL1PTGIRPTGDR | |
| SCHEMBL7110589 | 0.87 | CHRM4 (0.38) | ATMTDP1L3MBTL1PTGIRPTGDR | |
| SCHEMBL7107854 | 0.85 | ATM (0.41) | ATMTDP1L3MBTL1PPARGPTGIR | |
| SCHEMBL7653394 | 0.82 | PTGIR (0.46) | TDP1L3MBTL1PTGIRPTGDR | |
| SCHEMBL7106168 | 0.81 | ATM (0.41) | ATMTDP1L3MBTL1PTGIRPTGDR | |
| SCHEMBL7110718 | 0.79 | CHRM4 (0.40) | ATMTDP1L3MBTL1PTGIRPTGDR | |
| SCHEMBL17092997 | 0.79 | ATM (0.53) | ATMTDP1L3MBTL1PPARGPTGIR | |
| SCHEMBL7104991 | 0.79 | ATM (0.41) | ATMTDP1L3MBTL1PPARGPTGIR | |
| SCHEMBL7105749 | 0.79 | ATM (0.41) | ATMTDP1L3MBTL1PTGIRPTGDR | |
| SCHEMBL7104169 | 0.78 | ATM (0.39) | ATMTDP1L3MBTL1PTGIRPTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1013639-B1 | Aryl carboxylic acid and tetrazole derivatives comprising a carbamoyloxy unit | HOFFMANN LA ROCHE (CH) | 2003-10-01 | — | — | EP | disclosed |