SCHEMBL7107870

SCHEMBL7107870

[CH2]C(C)Oc1ccc(C(C)(C)CC)cc1C(C)(C)CC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 6/20 0.50
NPSR1 Q6W5P4 5/20 0.50
SMN1; SMN2 Q16637 5/20 0.50
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
ALDH1A1 P00352 1/20 0.50
MAPT P10636 5/20 0.46
HTT P42858 3/20 0.46
UBE2N P61088 2/20 0.46
GLA P06280 1/20 0.46
MITF O75030 1/20 0.46
RAB9A P51151 4/20 0.42
RAD52 P43351 2/20 0.42
STAT3 P40763 1/20 0.42
RCE1 Q9Y256 1/20 0.42
APAF1 O14727 1/20 0.42
HSP90AA1 P07900 1/20 0.42
NOD2 Q9HC29 1/20 0.42
NPC1 O15118 3/20 0.40
LMNA P02545 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8980027 0.85 MAPK1 (0.48) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL7227225 0.84 MAPK1 (0.53) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL5489761 0.84 MAPK1 (0.50) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL5145846 0.81 MAPK1 (0.50) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL9770169 0.81 MAPK1 (0.47) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL988255 0.80 MAPK1 (0.55) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL8595779 0.80 MAPK1 (0.49) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL8473986 0.80 MAPK1 (0.57) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL28378701 0.80 MAPK1 (0.55) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL10360547 0.80 MAPK1 (0.46) MAPK1NPSR1SMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1483732-A Novel BIS Au (I) sensitizers and their synthesis ��˹���´﹫˾ 2004-03-24 CN disclosed
US-6638701-B1 Element containing pyrazolotriazole coupler having certain carbonamido containing substituent that provides red dye having improved light stability EASTMAN KODAK COMPANY 2003-10-28 US disclosed
EP-1353222-A1 Photographic element containing azole couplers EASTMAN KODAK COMPANY (US) 2003-10-15 EP disclosed
US-6521397-B1 Support bearing light sensitive silver halide emulsion layer having associated such as 2-benzoazoacetoitrile derivative dye forming coupler; improved absorption maximum and color gamut EASTMAN KODAK COMPANY 2003-02-18 US disclosed
US-6197071-B1 HAIR DYES; LIGHT STABILITY; COLOR PHOTOGRAPHY EASTMAN KODAK COMPANY 2001-03-06 US disclosed
US-6140033-A SUPPORT WITH SILVER HALIDE EMULSIONS WITH COUPLERS EASTMAN KODAK COMPANY (US) 2000-10-31 US disclosed
EP-1014185-A1 Photographic element, pyrazolazole coupler, method for it's preparation and an azomethine dye EASTMAN KODAK COMPANY (US) 2000-06-28 EP disclosed
EP-0193397-B1 LIGHT-SENSITIVE SILVER HALIDE COLOR PHOTOGRAPHIC MATERIAL KONICA CORPORATION (JP) 1990-11-14 EP disclosed
US-4894322-A PYRAZOLTRIAZOLE COMPOUNDS, DEVELOPMENT KONICA CORPORATION (JP) 1990-01-16 US disclosed
US-4868100-A IMPROVED COLOR REPRODUCTIBILITY KONICA CORPORATION (JP) 1989-09-19 US disclosed
EP-0193397-A2 Light-sensitive silver halide color photographic material KONICA CORPORATION (JP) 1986-09-03 EP disclosed