SCHEMBL988255

SCHEMBL988255

[CH2]Oc1ccc(C(C)(C)CC)cc1C(C)(C)CC

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 6/20 0.55
NPSR1 Q6W5P4 5/20 0.55
SMN1; SMN2 Q16637 5/20 0.55
MEN1 O00255 4/20 0.55
KMT2A Q03164 4/20 0.55
ALDH1A1 P00352 1/20 0.55
MAPT P10636 5/20 0.50
HTT P42858 3/20 0.50
UBE2N P61088 2/20 0.50
GLA P06280 1/20 0.50
MITF O75030 1/20 0.50
RAB9A P51151 4/20 0.45
RAD52 P43351 2/20 0.45
STAT3 P40763 1/20 0.45
RCE1 Q9Y256 1/20 0.45
APAF1 O14727 1/20 0.45
HSP90AA1 P07900 1/20 0.45
NOD2 Q9HC29 1/20 0.45
NPC1 O15118 3/20 0.40
LMNA P02545 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9769334 0.86 MAPK1 (0.44) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL8473986 0.85 MAPK1 (0.57) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL8655138 0.84 MAPK1 (0.56) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL8598929 0.83 MAPK1 (0.59) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL8470405 0.82 MAPK1 (0.67) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL10105923 0.82 MAPK1 (0.55) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL133717 0.81 MAPK1 (0.54) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL29443083 0.81 MAPK1 (0.54) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
Propane SCHEMBL10703212 0.81 MAPK1 (0.54) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL75897 0.80 MAPK1 (0.59) MAPK1NPSR1SMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 226 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7312337-B2 Oxadiazoles and their manufacture EASTMAN KODAK COMPANY (US) 2007-12-25 US claimed
US-7268235-B2 Method for preparation of N-pyrazolylamidoximes EASTMAN KODAK COMPANY (US) 2007-09-11 US claimed
US-20060074245-A1 Method for preparation of N-pyrazolylamidoximes EASTMAN KODAK COMPANY 2006-04-06 US claimed
US-20060069262-A1 Oxadiazoles and their manufacture EASTMAN KODAK COMPANY 2006-03-30 US claimed
US-6280919-B1 Photographic element containing a stable aryloxypyrazolone coupler and process employing the same EASTMAN KODAK COMPANY 2001-08-28 US claimed
US-6156490-A Photographic element containing a stable aryloxypyrazolone coupler and process employing same EASTMAN KODAK COMPANY (US) 2000-12-05 US claimed
US-5063148-A Bicyclic pyrazole magenta couplers and a diphenol-type stabilizer provide improved colorfastness and reproduction; free from yellow stains KONICA CORPORATION (JP) 1991-11-05 US claimed
EP-0391341-A2 Silver halide light-sensitive photographic material KONICA CORPORATION (JP) 1990-10-10 EP claimed
EP-1832633-B1 Ink-jet recording ink set and ink-jet recording method FUJIFILM CORP (JP) 2016-11-30 EP disclosed
EP-1866165-B1 INKJET-RECORDING INK SET, INKJET-RECORDING INK AND INKJET IMAGE-RECORDING METHOD FUJIFILM CORP (JP) 2015-08-26 EP disclosed
EP-1874879-B1 INK JET RECORDING INK SET AND INK JET IMAGE RECORDING METHOD FUJIFILM CORP (JP) 2013-05-15 EP disclosed
EP-1866166-B1 INK SET FOR INK JET RECORDING, INK FOR INK JET RECORDING, AND INK JET IMAGE RECORDING METHOD FUJIFILM CORP (JP) 2012-10-24 EP disclosed
US-8197051-B2 Ink jet recording ink set and ink jet image recording method FUJIFILM CORPORATION (JP) 2012-06-12 US disclosed
US-8061830-B2 Ink-jet recording ink set and ink-jet recording method FUJIFILM CORPORATION (JP) 2011-11-22 US disclosed
US-4255509-A NAPHTHYL-AZO-PHENYL COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1981-03-10 US disclosed
US-4250246-A MAGENTA DYE-RELEASING REDOX COMPOUND; COLORFASTNESS FUJI PHOTO FILM CO., LTD. (JP) 1981-02-10 US disclosed
US-4246414-A INTERMEDIATE FOR DYE RELEASING REDOX COMPOUND SUITABLE FOR USE IN COLOR DIFFUSION TRANSFER FUJI PHOTO FILM CO., LTD. (JP) 1981-01-20 US disclosed
US-4245028-A CONTAINING AN AZO DYE RELEASING REDOX COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1981-01-13 US disclosed
US-4233237-A CHEMICAL INTERMEDIATE OF A DYE RELEASING COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1980-11-11 US disclosed
US-4145219-A HIGH SPEED SILVER HALIDE EMULSION CONTAINING DEVELOPMENT INHIBITOR RELEASING (DIR) COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1979-03-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060069262-A1 Oxadiazoles and their manufacture OXA1L, CYP1B1, OXER1 MAPK1 1092/4885NPSR1 2618/4885SMN1; SMN2 1897/4885
US-20060074245-A1 Method for preparation of N-pyrazolylamidoximes KCNH1, KCNJ2, KCNH2 MAPK1 1689/4885NPSR1 980/4885SMN1; SMN2 3121/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.