Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 1/20 | 0.35 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 4/20 | 0.35 |
| ▸ | PPARA | Q07869 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL218375 | 0.77 | ALDH1A1 (0.42) | ENPP3ENPP1ALDH1A1CYP3A4HPGD | |
| SCHEMBL215411 | 0.73 | CHRNB4 (0.37) | PPARGPPARAALDH1A1CYP3A4HPGD | |
| SCHEMBL216444 | 0.71 | CNR1 (0.35) | PPARGPPARAALDH1A1CYP3A4HPGD | |
| SCHEMBL2958680 | 0.69 | CNR1 (0.39) | ALOX15GAA | |
| SCHEMBL2971768 | 0.69 | ALDH1A1 (0.46) | ENPP3ENPP1ALDH1A1CYP3A4HPGD | |
| SCHEMBL2963519 | 0.68 | CNR1 (0.43) | MAPTALOX15 | |
| SCHEMBL216214 | 0.67 | ALDH1A1 (0.41) | ALDH1A1CYP3A4HPGDTSHRKEAP1 | |
| SCHEMBL2967708 | 0.67 | CNR1 (0.44) | ALDH1A1HPGDNPC1MAPTRAB9A | |
| SCHEMBL2975165 | 0.67 | CNR1 (0.44) | ALDH1A1HPGDNPC1MAPTRAB9A | |
| SCHEMBL2964841 | 0.67 | CNR1 (0.44) | ALDH1A1HPGDNPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1053263-B1 | CATALYST SYSTEM | BASELL POLYOLEFINE GMBH (DE) | 2003-10-01 | — | — | EP | claimed |