Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.66 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.66 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.66 |
| ▸ | S1PR2 | O95136 | 8/20 | 0.59 |
| ▸ | S1PR1 | P21453 | 8/20 | 0.59 |
| ▸ | S1PR3 | Q99500 | 8/20 | 0.59 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.59 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.59 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.52 |
| ▸ | ANPEP | P15144 | 1/20 | 0.49 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.46 |
| ▸ | SAT1 | P21673 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9320338 | 1.00 | LPAR3 (0.66) | LPAR3LPAR1LPAR2S1PR2S1PR1 | |
| SCHEMBL27788145 | 1.00 | LPAR3 (0.66) | LPAR3LPAR1LPAR2S1PR2S1PR1 | |
| SCHEMBL5978775 | 0.98 | LPAR3 (0.62) | LPAR3LPAR1LPAR2S1PR2S1PR1 | |
| Phosphoric Acid Monododecyl Ester SCHEMBL8438347 | 0.93 | LPAR3 (0.78) | LPAR3LPAR1LPAR2S1PR2S1PR1 | |
| SCHEMBL28359280 | 0.93 | LPAR3 (0.78) | LPAR3LPAR1LPAR2S1PR2S1PR1 | |
| Phosphoric Acid Monododecyl Ester SCHEMBL7122511 | 0.93 | LPAR3 (0.78) | LPAR3LPAR1LPAR2S1PR2S1PR1 | |
| SCHEMBL30954787 | 0.93 | LPAR3 (0.78) | LPAR3LPAR1LPAR2S1PR2S1PR1 | |
| SCHEMBL28883677 | 0.93 | LPAR3 (0.78) | LPAR3LPAR1LPAR2S1PR2S1PR1 | |
| SCHEMBL13400489 | 0.92 | LPAR3 (0.59) | LPAR3LPAR1LPAR2S1PR2S1PR1 | |
| SCHEMBL31325188 | 0.89 | LPAR3 (0.78) | LPAR3LPAR1LPAR2S1PR2S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030083313-A1 | Treatment of breast cancer with a liposome mixture comprising an antineoplastic alkylphospholipid and water- or lipid-soluble antiestrogen agents | MAX-DELBRUCK-CENTRUM FUR MOLEKULARE MEDIZIN (DE) | 2003-05-01 | — | — | US | disclosed |