Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VIPR2 | P41587 | 19/20 | 0.61 |
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17038236 | 0.88 | VIPR2 (0.69) | VIPR2MMP9 | |
| SCHEMBL15713788 | 0.84 | VIPR2 (0.62) | VIPR2MMP9 | |
| SCHEMBL15713510 | 0.84 | VIPR2 (0.68) | VIPR2MMP9 | |
| SCHEMBL15713508 | 0.83 | VIPR2 (0.65) | VIPR2MMP9 | |
| SCHEMBL7300250 | 0.83 | VIPR2 (0.70) | VIPR2MMP1MMP2MMP9MMP8 | |
| SCHEMBL7300253 | 0.83 | VIPR2 (0.70) | VIPR2MMP1MMP2MMP9MMP8 | |
| SCHEMBL7111515 | 0.82 | VIPR2 (0.62) | VIPR2 | |
| SCHEMBL6466122 | 0.82 | VIPR2 (0.69) | VIPR2MMP1MMP2MMP9MMP8 | |
| SCHEMBL17038237 | 0.82 | VIPR2 (0.67) | VIPR2MMP9 | |
| Hydrochloric Acid SCHEMBL7108282 | 0.81 | VIPR2 (0.65) | VIPR2MMP1MMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0766674-B1 | NEW HIV PROTEASE INHIBITORS | MERCK & CO INC (US) | 2003-10-15 | — | — | EP | disclosed |
| EP-0766674-A4 | NEW HIV PROTEASE INHIBITORS | MERCK & CO INC (US) | 1997-09-03 | — | — | EP | disclosed |
| EP-0766674-A1 | NEW HIV PROTEASE INHIBITORS | MERCK & CO. INC. (US) | 1997-04-09 | — | — | EP | disclosed |
| WO-1995035286-A1 | NEW HIV PROTEASE INHIBITORS | MERCK & CO., INC. (US) | 1995-12-28 | — | — | WO | disclosed |
| US-5476874-A | Oligopeptide analogs containing sulfonamide, urea, carbamate, | MERCK & CO., INC. (US) | 1995-12-19 | — | — | US | disclosed |