Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VIPR2 | P41587 | 18/20 | 0.70 |
| ▸ | MMP9 | P14780 | 2/20 | 0.64 |
| ▸ | MMP1 | P03956 | 1/20 | 0.62 |
| ▸ | MMP2 | P08253 | 1/20 | 0.62 |
| ▸ | MMP8 | P22894 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7300250 | 1.00 | VIPR2 (0.70) | VIPR2MMP9MMP1MMP2MMP8 | |
| SCHEMBL6466122 | 0.97 | VIPR2 (0.69) | VIPR2MMP9MMP1MMP2MMP8 | |
| SCHEMBL15713420 | 0.93 | VIPR2 (0.66) | VIPR2MMP9 | |
| SCHEMBL15714613 | 0.93 | VIPR2 (0.66) | VIPR2MMP9 | |
| SCHEMBL7293187 | 0.92 | MMP9 (0.74) | VIPR2MMP9MMP1MMP2MMP8 | |
| SCHEMBL7293189 | 0.92 | MMP9 (0.74) | VIPR2MMP9MMP1MMP2MMP8 | |
| SCHEMBL15713978 | 0.92 | VIPR2 (0.64) | VIPR2MMP9 | |
| SCHEMBL15713701 | 0.91 | VIPR2 (0.65) | VIPR2MMP9 | |
| SCHEMBL6468083 | 0.90 | VIPR2 (0.62) | VIPR2MMP9MMP2 | |
| SCHEMBL6469322 | 0.90 | VIPR2 (0.64) | VIPR2MMP9MMP1MMP2MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0480714-A2 | HIV protease inhibitors having symmetrical structure | MERCK & CO. INC. (US) | 1992-04-15 | — | — | EP | claimed |
| JP-5148205-A | — | — | None | — | — | JP | disclosed |
| JP-H05148205-A | HIV PROTEASE INHIBITOR HAVING SYMMETRICAL STRUCTURE | MERCK & CO INC | 1993-06-15 | — | — | JP | disclosed |
| EP-0480714-A2 | HIV protease inhibitors having symmetrical structure | MERCK & CO. INC. (US) | 1992-04-15 | — | — | EP | disclosed |